Edward I. Solomon

TL;DR: Spectroscopic methods show that vibrations in the cysteine side chain of the T1 Cu site and the protein backbone couple to the Cu-S vibration provide a possible mechanism for regulating intramolecular T1 to TNC ET in NI and partially reduced enzyme forms for efficient turnover.

TL;DR: A geometric structure and more complete electronic description of the high-spin heme-peroxo-copper complexes 1 and 2 and the phenoxyl radical generated by the H-atom abstraction was either directly detected by electron paramagnetic resonance spectroscopy using phenols that produce stable radicals or indirectly detected by the coupling product of two Phenoxyl radicals.

TL;DR: A macrocyclic ligand (L4–) comprising two pyridine(dicarboxamide) donors was used to target reactive copper species relevant to proposed intermediates in catalytic hydrocarbon oxidations by particulate methane monooxygenase and heterogeneous zeolite systems to provide the first precedence for such moieties as oxidation catalysis intermediates.

TL;DR: In this study, NO is used as an O(2) analogue to probe the effects of α-keto acid binding in 4-hydroxyphenylpyruvate dioxygenase (HPPD) and a combination of EPR, UV-vis absorption, magnetic circular dichroism (MCD), and variable-temperature, variable-field (VTVH) MCD spectroscopies in conjunction with computational models are used.

TL;DR: These studies define the steric and intrinsic electronic contributions to the reaction barriers and establish that both the S = 1 and S = 2 surfaces have significant steric contributions due to the different directionalities of substrate approach and thus similar intrinsic reactivities.