E
Effie W. Petersdorf
Researcher at Fred Hutchinson Cancer Research Center
Publications - 242
Citations - 20326
Effie W. Petersdorf is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Transplantation & Human leukocyte antigen. The author has an hindex of 67, co-authored 234 publications receiving 18917 citations. Previous affiliations of Effie W. Petersdorf include University of Oxford & National Taiwan University.
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Journal ArticleDOI
Clinical significance of donor-recipient HLA matching on survival after myeloablative hematopoietic cell transplantation from unrelated donors.
TL;DR: The application of unrelated donor hematopoietic cell transplantation can be expanded with the use of mismatched donors if human leukocyte antigen (HLA) disparity does not lead to increased morbidity and mortality.
Journal ArticleDOI
Unrelated donor or autologous marrow transplantation for treatment of acute leukemia
Alessandro Busca,Claudio Anasetti,G Anderson,FR Appelbaum,Buckner Cd,Kristine Doney,P.J. Martin,Effie W. Petersdorf,Jean E. Sanders,John A. Hansen +9 more
TL;DR: Unrelated donor transplants appear no less effective than autologous transplants to achieve long-term survival and may be more effective in eradicating leukemia in patients who have failed conventional chemotherapy.
Journal ArticleDOI
Evaluation of a CD25-specific immunotoxin for prevention of graft-versus-host disease after unrelated marrow transplantation
Paul J. Martin,Paul J. Martin,Ji Pei,Ted Gooley,Claudio Anasetti,Claudio Anasetti,Frederick R. Appelbaum,Frederick R. Appelbaum,Joachim Deeg,Joachim Deeg,John A. Hansen,John A. Hansen,Richard A. Nash,Richard A. Nash,Effie W. Petersdorf,Effie W. Petersdorf,Rainer Storb,Rainer Storb,Victor Ghetie,John Schindler,Ellen S. Vitetta +20 more
TL;DR: Results are consistent with the hypothesis that cyclosporine protected alloactivated donor T cells from the effects of the immunotoxin, whereas the CD25+ T-regulatory cells remained susceptible, causing an unexpected exacerbation of acute GVHD.
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HLA-allele matched unrelated donors compared to HLA-matched sibling donors: role of cell source and disease risk category.
Ann E. Woolfrey,Ann E. Woolfrey,Stephanie J. Lee,Stephanie J. Lee,Ted Gooley,Mari Malkki,Paul J. Martin,Paul J. Martin,John M. Pagel,John M. Pagel,John A. Hansen,John A. Hansen,Effie W. Petersdorf,Effie W. Petersdorf +13 more
TL;DR: In this article, the authors performed a retrospective analysis of 1448 patients with high-risk or advanced hematologic malignancies given T-replete grafts after myeloablative conditioning.
Journal ArticleDOI
Tissue typing in support of unrelated hematopoietic cell transplantation.
TL;DR: Improved HLA matching of potential unrelated donors has led to clinical results that begin to compare favorably with that of HLA-identical sibling transplants.