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Eirini I. Rigopoulou

Researcher at RMIT University

Publications -  142
Citations -  4776

Eirini I. Rigopoulou is an academic researcher from RMIT University. The author has contributed to research in topics: Primary biliary cirrhosis & Autoimmune hepatitis. The author has an hindex of 38, co-authored 132 publications receiving 4293 citations. Previous affiliations of Eirini I. Rigopoulou include University College London & University of Cambridge.

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Twin studies in autoimmune disease: genetics, gender and environment.

TL;DR: Future research is encouraged not only in the analysis of twins with autoimmune disease, but also in regards to epigenetic factors or rare variants that may be discovered with next-generation sequencing.
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Resolution of chronic hepatitis B and anti-HBs seroconversion in humans by adoptive transfer of immunity to hepatitis B core antigen.

TL;DR: This study provides the first evidence in humans that transfer of hepatitis B core antigen-reactive T cells is associated with resolution of chronic HBV infection, and deserves further investigation in patients with chronic hepatitis B.
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Mycophenolate for the treatment of autoimmune hepatitis: Prospective assessment of its efficacy and safety for induction and maintenance of remission in a large cohort of treatment-naïve patients

TL;DR: MMF seems safe and effective as first-line therapy in inducing and maintaining remission in treatment-naive patients with AIH, having a significant and rapid steroid sparing effect as attested by the fact that so far, 37% of AIH patients achieved CR off prednisolone.
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Microbial mimics are major targets of crossreactivity with human pyruvate dehydrogenase in primary biliary cirrhosis

TL;DR: This report reports on a study testing reactivity and competitive cross-reactivity against these respective peptides, and in some cases the parent protein, using sera from 55 patients with PBC, compared to reactivity of 190 pathological and 28 healthy controls.