E
Eleonora Petrucci
Researcher at Istituto Superiore di Sanità
Publications - 38
Citations - 1987
Eleonora Petrucci is an academic researcher from Istituto Superiore di Sanità. The author has contributed to research in topics: Ovarian cancer & CD34. The author has an hindex of 25, co-authored 37 publications receiving 1881 citations. Previous affiliations of Eleonora Petrucci include Thomas Jefferson University.
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Journal ArticleDOI
A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis
Catherine Labbaye,Isabella Spinello,Maria Teresa Quaranta,Elvira Pelosi,Luca Pasquini,Eleonora Petrucci,Mauro Biffoni,Eugenia Rosa Nuzzolo,Monia Billi,Robin Foà,Ercole Brunetti,Francesco Grignani,Ugo Testa,Cesare Peschle +13 more
TL;DR: The data indicate that megakaryopoiesis is controlled by a cascade pathway, in which PLZF suppresses miR-146a transcription and thereby activates CXCR4 translation.
Journal ArticleDOI
Circulating haemopoietic and endothelial progenitor cells are decreased in COPD
Paolo Palange,Ugo Testa,Alice Huertas,L. Calabrò,R. Antonucci,Eleonora Petrucci,Elvira Pelosi,Luca Pasquini,A Satta,Morici G,M A Vignola,Maria R. Bonsignore +11 more
TL;DR: Circulating CD34+ cells and endothelial progenitors were decreased in chronic obstructive pulmonary disease patients and could be correlated with disease severity.
Journal ArticleDOI
The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor.
Roberta Riccioni,Maria Luisa Dupuis,Manuela Bernabei,Eleonora Petrucci,Luca Pasquini,Gualtieri Mariani,Maurizio Cianfriglia,Ugo Testa +7 more
TL;DR: It is reported that salinomycin acts as a potent inhibitor of multidrug resistance gp170, as evidenced through drug efflux assays in MDR cancer cell lines overexpressing P-gp (CEM-VBL 10 and CEM- VBL 100; A2780/ADR).
Journal ArticleDOI
Autocrine-paracrine VEGF loops potentiate the maturation of megakaryocytic precursors through Flt1 receptor.
Ida Casella,Tiziana Feccia,Tiziana Feccia,C Chelucci,C Chelucci,Paola Samoggia,Paola Samoggia,Germana Castelli,Germana Castelli,R Guerriero,R Guerriero,Isabella Parolini,Isabella Parolini,Eleonora Petrucci,Eleonora Petrucci,Elvira Pelosi,Elvira Pelosi,Ornella Morsilli,Ornella Morsilli,Marco Gabbianelli,Marco Gabbianelli,Ugo Testa,Ugo Testa,Cesare Peschle,Cesare Peschle +24 more
TL;DR: The results suggest that in the hematopoietic microenvironment an autocrine VEGF loop contributes to optimal Mk maturation through Flt1 and a paracrine loop involving V EGF release by E precursors may also operate.
Journal ArticleDOI
Ovarian Cancers: Genetic Abnormalities, Tumor Heterogeneity and Progression, Clonal Evolution and Cancer Stem Cells
TL;DR: Ovarian cancer cells have an intrinsic plasticity, thus explaining that in a single tumor more than one cell subpopulation, may exhibit tumor-initiating capacity, and improvements in the understanding of the molecular and cellular basis of ovarian cancers should lead to more efficacious treatments.