Elisabeth Baloch

TL;DR: Regional LNA-92a delivery reduces miR- 92a levels and infarct size and postischemic loss of function and might be a novel therapeutic tool to preserve cardiac function after ischemia.

TL;DR: CT- derived MBF measurements at rest and stress with varying degrees of coronary stenosis show a valid difference but an underestimated correlation with microsphere-derived MBF in a porcine animal model.

TL;DR: At higher degrees of coronary stenosis, bothMBFCT and SPE permit an accurate prediction of segmental myocardial hypoperfusion, however, accuracy of MBFCT is higher than that of SPE at 50% stenosis and can be increased by adenosine stress at both degrees of stenosis.

TL;DR: In a large animal model, CT-derived parameters of myocardial perfusion may enable detection and differentiation of ischemic and infarcted myocardium.

TL;DR: Histological analysis showed pronounced left atrial and left ventricular fibrosis demonstrating a structural substrate underlying the increased arrhythmogenicity of atrial arrhythmia episodes including AF in IHF pigs, and selective ventricular infarction via LAD occlusion causes haemodynamic alterations inducing structural atrial remodeling which results in increased atrial fibrosis as the arrhogenic atrial substrate in pigs with IHF.