E
Emi E. Nakayama
Researcher at Osaka University
Publications - 98
Citations - 2460
Emi E. Nakayama is an academic researcher from Osaka University. The author has contributed to research in topics: Virus & Dengue fever. The author has an hindex of 25, co-authored 82 publications receiving 2060 citations. Previous affiliations of Emi E. Nakayama include Mahidol University.
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Journal ArticleDOI
Polymorphism in RANTES chemokine promoter affects HIV-1 disease progression.
Huanliang Liu,David M. Chao,Emi E. Nakayama,Hitomi Taguchi,Mieko Goto,Xiaomi Xin,Junki Takamatsu,Hidehiko Saito,Yoshihide Ishikawa,Tatsuya Akaza,Takeo Juji,Yutaka Takebe,Takeshi Ohishi,Katsuyuki Fukutake,Yoshikazu Maruyama,Shinji Yashiki,Shunro Sonoda,Tetsuya Nakamura,Yoshiyuki Nagai,Aikichi Iwamoto,Tatsuo Shioda +20 more
TL;DR: Functional analyses of RantES promoter activity indicated that the RANTES-28G mutation increases RANTes expression in HIV-1-infected individuals and thus delays the progression of the HIV- 1 disease.
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Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1α (SDF-1α) and SDF-1β are abolished by CD26/dipeptidyl peptidase IV-mediated cleavage
Tatsuo Shioda,Hiroyuki S. Kato,Yukano Ohnishi,Kei Tashiro,Masaya Ikegawa,Emi E. Nakayama,Huiling Hu,Atsushi Kato,Yuko Sakai,Huanliang Liu,Tasuku Honjo,Akio Nomoto,Aikichi Iwamoto,Chikao Morimoto,Yoshiyuki Nagai +14 more
TL;DR: The data suggest that CD26-mediated cleavage of SDF-1α and Sdf-1β likely occurs in human bodies and promotes HIV-1 replication and disease progression, and may also explain why memory function of CD4+ cells is preferentially lost in HIV- 1 infection.
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An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies
Yafei Liu,Wai Tuck Soh,Jun-ichi Kishikawa,Mika Hirose,Emi E. Nakayama,Songling Li,Miwa Sasai,Tatsuya Suzuki,Asa Tada,Akemi Arakawa,Sumiko Matsuoka,Kanako Akamatsu,Makoto Matsuda,Chikako Ono,Shiho Torii,Kazuki Kishida,Hui Jin,Wataru Nakai,Noriko Arase,Atsushi Nakagawa,Maki Matsumoto,Yukoh Nakazaki,Yasuhiro Shindo,Masako Kohyama,Keisuke Tomii,Koichiro Ohmura,Shiro Ohshima,Toru Okamoto,Masahiro Yamamoto,Hironori Nakagami,Yoshiharu Matsuura,Takayuki Kato,Masato Okada,Daron M. Standley,Tatsuo Shioda,Hisashi Arase +35 more
TL;DR: In this paper, a series of anti-spike monoclonal antibodies from coronavirus disease 2019 (COVID-19) patients were screened and found that some of the antibodies against the N-terminal domain induced the open conformation of RBD and thus enhanced the binding capacity of the spike protein to ACE2 and infectivity of SARS-CoV-2.
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A CCR2-V64I polymorphism affects stability of CCR2A isoform
TL;DR: It is proposed that the increased ability of CCR2A-64I to down-modulate CCR5 expression might be a possible cause of a delay in HIV-1 disease progression in patients with this allele.
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HLA-Cw*04 allele associated with nevirapine-induced rash in HIV-infected Thai patients
Sirirat Likanonsakul,Tippawan Rattanatham,Siriluk Feangvad,Sumonmal Uttayamakul,Wisit Prasithsirikul,Preecha Tunthanathip,Emi E. Nakayama,Tatsuo Shioda +7 more
TL;DR: This study suggests that HLA-Cw*04 is associated with rash in nevirapine treated Thais, and patients with alleles associated with ne virapine-induced rash should be started on anti-retroviral therapy without nevirAPine.