E
Enrica Bordignon
Researcher at Ruhr University Bochum
Publications - 83
Citations - 3573
Enrica Bordignon is an academic researcher from Ruhr University Bochum. The author has contributed to research in topics: Electron paramagnetic resonance & Site-directed spin labeling. The author has an hindex of 31, co-authored 77 publications receiving 3062 citations. Previous affiliations of Enrica Bordignon include ETH Zurich & University of Bari.
Papers
More filters
Journal ArticleDOI
Rotamer libraries of spin labelled cysteines for protein studies
TL;DR: It is shown here that libraries of about 200 rotamers, obtained by iterative projection of a long MD trajectory of the free spin label onto a set of canonical dihedral angles, provide a representation of the underlying trajectory adequate for EPR distance measurements.
Journal ArticleDOI
Structural Model of Active Bax at the Membrane
Stephanie Bleicken,Gunnar Jeschke,Carolin Stegmueller,Carolin Stegmueller,Carolin Stegmueller,Raquel Salvador-Gallego,Raquel Salvador-Gallego,Raquel Salvador-Gallego,Ana J. García-Sáez,Ana J. García-Sáez,Ana J. García-Sáez,Enrica Bordignon,Enrica Bordignon +12 more
TL;DR: It is shown that active Bax is organized at the membrane as assemblies of dimers, and each monomer contains a more flexible piercing domain involved in interdimer interactions and pore formation.
Journal ArticleDOI
Molecular details of Bax activation, oligomerization, and membrane insertion.
Stephanie Bleicken,Mirjam Classen,Pulagam V. L. Padmavathi,Takashi Ishikawa,Kornelius Zeth,Heinz-Juergen Steinhoff,Enrica Bordignon +6 more
TL;DR: Bax and Bid are pro-apoptotic members of the Bcl-2 protein family and Bid was shown to activate Bax independently of the stoichiometric ratio, suggesting that Bid has a catalytic function and that the interaction with Bax is transient.
Journal ArticleDOI
High sensitivity and versatility of the DEER experiment on nitroxide radical pairs at Q-band frequencies
Yevhen Polyhach,Enrica Bordignon,René Tschaggelar,Sandhya Gandra,Adelheid Godt,Gunnar Jeschke +5 more
TL;DR: The performance improvement that can be achieved at Q-band frequencies (34.5 GHz) using a high-power spectrometer is quantified and it is demonstrated that a commercial Q- band spectrometers can be readily adjusted to the high- power operation.
Journal ArticleDOI
The Structure and Regulation of Human Muscle α-Actinin
Euripedes de Almeida Ribeiro,Nikos Pinotsis,Andrea Ghisleni,Anita Salmazo,Petr V. Konarev,Julius Kostan,Björn Sjöblom,Claudia Schreiner,Anton A. Polyansky,Anton A. Polyansky,Eirini A. Gkougkoulia,Mark R. Holt,Finn Lillelund Aachmann,Bojan Žagrović,Enrica Bordignon,Enrica Bordignon,Katharina F. Pirker,Dmitri I. Svergun,Mathias Gautel,Kristina Djinović-Carugo,Kristina Djinović-Carugo +20 more
TL;DR: The structure provides insight into the phosphoinositide-based mechanism controlling its interaction with sarcomeric proteins such as titin, lays a foundation for studying the impact of pathogenic mutations at molecular resolution, and is likely to be broadly relevant for the regulation of spectrin-like proteins.