Showing papers in "Virology in 1978"

TL;DR: The RNA of the human influenza virus Singapore (H2N2) strain has been labeled in vivo by phosphorus-32 and separated by polyacrylamide gel electrophoresis into eight segments, which were correlated to the corresponding gene functions and/or proteins.

TL;DR: The susceptibility of ducks to infection with human and avian strains of influenza virus and the possibility of transmission to animal species through the water supply suggests that ducks may be important in the ecology of influenza viruses.

TL;DR: Isolation of variants from the three phenotypic forms has shown that each of the infectious forms is heterogeneous and that no segregation of genotypes among the three forms was evident.

TL;DR: Using this improved method, ts and hr mutations in intact DNA have been rescued with restriction endonuclease fragments of DNA bearing the corresponding wild-type genetic markers and a number of mutations have been located unequivocally within the left quarter of the genome.

TL;DR: Polypeptide identification was made not only on the basis of electrophoretic migration rates in both the phosphate- and Tri-glycine (Laemmli)-based polyacrylamide gel systems, but also on the based of comparing peptide profiles of in vitro translation products and authentic reovirus polypeptides after digestion with staphylococcal V8 protease.

TL;DR: Serological and virological surveillance of swine during 1976-77 showed that Hsw1N1 influenza viruses were prevalent throughout the swine population of the U.S., particularly in the northern states.

TL;DR: The available evidence suggests that the synthesis of polypeptide 4 requires “early” protein synthesis, which is distinct from the eight defined influenza virus gene products.

TL;DR: Host-range mutants of human adenovirus type 5, selected for their ability to grow preferentially on transformed human embryo kidney cells and shown to fall into two complementation groups, have been tested for ability to transform rat embryo, rat embryo brain, and baby rat kidney cells.

TL;DR: Virus-specific RNA molecules synthesized in BHK 21 vertebrate cells and in Aedes albopictus mosquito cells infected with the flaviviruses Uganda S or West Nile have been characterized.

TL;DR: A 32,000-dalton nucleic acid-binding protein (p32), possessing DNA endonuclease activity, has been identified in avian myeloblastosis virus (AMV) and Rous sarcoma virus (Prague B strain) cores.

TL;DR: The structural polypeptides of eight insect baculoviruses were studied using vertical slab polyacrylamide gel electrophoresis and quantitative and qualitative differences were documented to exist inpolypeptide composition.

TL;DR: The genetic homology between various HIN1 strains was determined by hybridization techniques using isolated RNA segments compatible with the view that an HIM strain from 1950 survived somewhere with few mutations for 27 years and then reappeared as a virus pathogenic for man.

TL;DR: The presence of HA0 in smooth membranes of TM-treated cells suggests that neither glycosylation nor sulfation is essential for membrane association or migration of HA from rough to smooth membranes.

TL;DR: It is determined that the hemagglutinating properties of reovirus are a function of the σ1 outer capsid polypeptide, the polypePTide encoded in the S1 dsRNA segment of the virus.

TL;DR: Differences in RNA migration pattern were observed among human strains as well as between human and animal strains; the number of interspecies differences was greater than thenumber of intraspecies differences.

TL;DR: Results support an autoprotease model for the co-translational cleavage of Sindbis virus capsid proteins in pulse-chase experiments and inhibit capsid production and larger polypeptides accumulate.

TL;DR: Recombinants derived from crosses between reovirus serotypes 1, 2, and 3 were utilized to identify the ds RNA segments encoding polypeptides of the μ and σ size classes, and polypePTide species μ2 has been conclusively identified as a structural component of the reov virus core.

TL;DR: Despite their different fingerprints (and hence RNA sequences), CEV, CSV, and two strains of PSTV affect a common biological process not affected by ChCMV.

TL;DR: It is shown that cell fusion is the major factor in early cell death caused by measles virus, but that cell death ultimately ensues in the absence of cell fusion, indicating another mechanism of measles virus-induced cell damage.

TL;DR: Trigeminal ganglia of mice infected with Herpes simplex virus were examined for the presence of viral-specific DNA and mRNA sequences at both acute (4–5 days postinoculation) and chronic stages of the infection.

TL;DR: Influenza A (HIND viruses isolated from man from May 1977 to about February 1978 are antigenically homogenous and resemble "Scandinavian" strains that co-circulated with “Liverpool” strains during epidemics in 1950/51.

TL;DR: The results suggest that expression of RNA sequences highly related to xenotropic virus might be important in the pathogenesis of F-MuLV-induced leukemia.

TL;DR: Virus assembly time in asynchronously infected cells (protoplasts from infected plants) was much shorter, the difference considered to be the time in synchronous infection needed for the completion of replication cycle events prerequisite to virus assembly.

TL;DR: It is postulated that 3-deazaadenosine inhibits virus activities by its ability to inhibit adenosylhomocysteine hydrolase, resulting in an inhibition of methylation reaction(s) required for virus growth and replication.

TL;DR: It is demonstrated that recombinants arise by physical reassortment of genome segments between parents by construction of a map of the serotypes correlating genome segments providing functions interchangeable between the Serotype 1, 2, and 3.

TL;DR: The results suggest that the A gene product of polyoma regulates transcription of early RNA, as has been suggested for SV40, and that the wild-type A-gene product overcomes the effect of the temperature-sensitive A-Gene product.

TL;DR: Six new phages active on Myxococcus xanthus have been isolated from cultures of myxobacteria, and they fall into three groups, one of which has long contractile tails, have a characteristic neutralization antigen, and resemble the previously described M×4.

TL;DR: Tryptic peptide maps of the crystallized neuraminidase heads of the Nederlands/68 and Hong Kong/68 strains were almost identical, suggesting that a virus closely related to the N Amsterdam/68 (H2N2) strain may have been the source of the neuramidase for the formation of the H3N2 Hong Kong subtype.

TL;DR: Findings show that uncoating of this virus took place within the nucleus and not at the site of the nuclear pores as suggested for some baculoviruses.

TL;DR: Analysis of [ 32 P]orthophosphate-labeled extracts of adenovirus 2 (AD2)-infected HeLa cells revealed three major adanovirus-specific phosphorylated species, of molecular weights 100,000, 72,000 and 33,000; none of the three major phosphoproteins is a structural component of purifiedadenovirions.