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Eric J. Murphy
Researcher at University of North Dakota
Publications - 104
Citations - 4529
Eric J. Murphy is an academic researcher from University of North Dakota. The author has contributed to research in topics: Fatty acid & Phospholipid. The author has an hindex of 38, co-authored 104 publications receiving 4214 citations. Previous affiliations of Eric J. Murphy include Texas A&M University & Florida State University College of Arts and Sciences.
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Journal ArticleDOI
Alpha-linolenic acid and its conversion to longer chain n-3 fatty acids: benefits for human health and a role in maintaining tissue n-3 fatty acid levels.
TL;DR: It is proposed, based upon previous work and that of others, that ALA is elongated and desaturated in a tissue-dependent manner and its dietary inclusion is critical for maintaining tissue long chain n-3 levels.
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Mitochondrial Lipid Abnormality and Electron Transport Chain Impairment in Mice Lacking α-Synuclein
Christopher E. Ellis,Eric J. Murphy,Drake C. Mitchell,Mikhail Y. Golovko,Fernando Scaglia,Gwendolyn Barceló-Coblijn,Robert L. Nussbaum +6 more
TL;DR: Altered membrane composition and structure and impaired complex I/III function in Snca −/− brain suggest a relationship between α-synuclein's role in brain lipid metabolism, mitochondrial function, and PD.
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Flaxseed oil and fish-oil capsule consumption alters human red blood cell n-3 fatty acid composition : a multiple-dosing trial comparing 2 sources of n-3 fatty acid
Gwendolyn Barceló-Coblijn,Eric J. Murphy,Rgia A. Othman,Mohammed H. Moghadasian,Tarek Kashour,James K Friel +5 more
TL;DR: The consumption of ALA-enriched supplements for 12 wk was sufficient to elevate erythrocyte EPA and docosapentaenoic acid content, which shows the effectiveness of AlA conversion and accretion into ery Throcytes.
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High-fat diet-induced juvenile obesity leads to cardiomyocyte dysfunction and upregulation of Foxo3a transcription factor independent of lipotoxicity and apoptosis.
David P. Relling,Lucy B. Esberg,Cindy X Fang,W. Thomas Johnson,Eric J. Murphy,Edward C. Carlson,Jack T. Saari,Jun Ren +7 more
TL;DR: The data show that high-fat diet-induced obesity resulted in impaired cardiomyocyte function, upregulated Foxo3a transcription factor and mitochondrial damage without overt lipotoxicity or apoptosis.
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Recent advances in membrane cholesterol domain dynamics and intracellular cholesterol trafficking
Friedhelm Schroeder,Andrey Frolov,Eric J. Murphy,Barbara P. Atshaves,John R. Jefferson,Lixia Pu,W. Gibson Wood,William B. Foxworth,Ann B. Kier +8 more
TL;DR: Based on the fundamental observation that cholesterol is not distributed uniformly in the cell, three key concepts have contributed to recent advances in this field: First, cholesterol is asymmetrically distributed across the cell surface plasma membrane, wherein it translocates rapidly.