E
Erik Gustafson
Researcher at Beth Israel Deaconess Medical Center
Publications - 14
Citations - 1548
Erik Gustafson is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Internal medicine & Genome. The author has an hindex of 6, co-authored 12 publications receiving 1502 citations. Previous affiliations of Erik Gustafson include Beckman Coulter & Brigham and Women's Hospital.
Papers
More filters
Journal ArticleDOI
Mapping and sequencing of structural variation from eight human genomes
Jeffrey M. Kidd,Gregory M. Cooper,William F. Donahue,Hillary S. Hayden,Nick Sampas,Tina Graves,Nancy F. Hansen,Brian Teague,Can Alkan,Francesca Antonacci,Eric Haugen,Troy Zerr,N. Alice Yamada,Peter Tsang,Tera L. Newman,Eray Tüzün,Ze Cheng,Heather Ebling,Nadeem Tusneem,Robert David,Will D. Gillett,Karen A. Phelps,Molly Weaver,David J. Saranga,Adrianne Brand,Wei Tao,Erik Gustafson,Kevin McKernan,Lin Chen,Maika Malig,Joshua D. Smith,Joshua M. Korn,Steven A. McCarroll,David Altshuler,Daniel A. Peiffer,Michael O. Dorschner,John A. Stamatoyannopoulos,David C. Schwartz,Deborah A. Nickerson,James C. Mullikin,Richard K. Wilson,Laurakay Bruhn,Maynard V. Olson,Rajinder Kaul,Douglas R. Smith,Evan E. Eichler +45 more
TL;DR: This work employs a clone-based method to interrogate intermediate structural variation in eight individuals of diverse geographic ancestry and provides the first high-resolution sequence map of human structural variation—a standard for genotyping platforms and a prelude to future individual genome sequencing projects.
Journal ArticleDOI
Epstein-Barr virus encodes a novel homolog of the bcl-2 oncogene that inhibits apoptosis and associates with Bax and Bak.
William L. Marshall,Ching Yim,Erik Gustafson,Thomas Graf,David R. Sage,Katherine Hanify,Louisa Williams,Joyce D. Fingeroth,Robert W. Finberg +8 more
TL;DR: Results indicate that Epstein-Barr virus encodes a second functional v-bcl-2, which may encode a protein that functions in preventing the apoptotic death of virus-infected cells.
Journal ArticleDOI
Detection of Kaposi's sarcoma herpesvirus DNA sequences in multiple myeloma bone marrow stromal cells.
Dharminder Chauhan,Ajit Bharti,Ajit Bharti,Noopur Raje,Noopur Raje,Erik Gustafson,Erik Gustafson,Geraldine S. Pinkus,Geraldine S. Pinkus,Jack L. Pinkus,Jack L. Pinkus,Gerrard Teoh,Gerrard Teoh,Teru Hideshima,Teru Hideshima,SP Treon,SP Treon,Joyce D. Fingeroth,Joyce D. Fingeroth,Kenneth C. Anderson,Kenneth C. Anderson +20 more
TL;DR: KSHV DNA sequences are detectable in BMSCs from the majority of MM patients, but that serologic responses to KSHV are not present, showing whether the lack of antibody response is caused by the absence of ongoing infection, the presence of a novel viral strain associated with MM, or underlying immunodeficiency in these patients.
Journal ArticleDOI
Characterization of an Acyclovir-Resistant Herpes Simplex Virus Type 2 Strain Isolated from a Premature Neonate
Ronda J. Oram,Daniel Marcellino,Daniel M. Strauss,Erik Gustafson,Christine L. Talarico,Adrienne K. Root,Prem L. Sharma,Kenneth Thompson,Joyce D. Fingeroth,Clyde S. Crumpacker,Betsy C. Herold +10 more
TL;DR: Acyclovir-resistant HSV-2 mutants can develop rapidly in neonatal infection and cause clinically significant disease, despite decreased replication in vitro and attenuated virulence in an animal model.
Patent
Methods of isolating nucleic acids using multifunctional group-coated solid phase carriers
TL;DR: In this paper, the mixture is combined with solid phase carriers having a surface comprising multiple functional groups one of which reversibly and selectively binds the target nucleic acid species, thereby producing a first combination.