E
Erik S. Barton
Researcher at Vanderbilt University
Publications - 19
Citations - 2763
Erik S. Barton is an academic researcher from Vanderbilt University. The author has contributed to research in topics: Virus latency & Viral replication. The author has an hindex of 17, co-authored 19 publications receiving 2592 citations. Previous affiliations of Erik S. Barton include Wake Forest University & Purdue University.
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Journal ArticleDOI
Herpesvirus latency confers symbiotic protection from bacterial infection
Erik S. Barton,Douglas W. White,Jason S. Cathelyn,Kelly A. Brett-McClellan,Michael Engle,Michael S. Diamond,Virginia L. Miller,Herbert W. Virgin +7 more
TL;DR: Whereas the immune evasion capabilities and lifelong persistence of herpesviruses are commonly viewed as solely pathogenic, the data suggest that latency is a symbiotic relationship with immune benefits for the host.
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Junction Adhesion Molecule Is a Receptor for Reovirus
Erik S. Barton,J. Craig Forrest,Jodi L. Connolly,James D. Chappell,Yuan Liu,Frederick J. Schnell,Asma Nusrat,Charles A. Parkos,Terence S. Dermody +8 more
TL;DR: Reovirus interaction with cell-surface receptors is a critical determinant of both cell-type specific tropism and virus-induced intracellular signaling events that culminate in cell death.
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Pathogenesis and host control of gammaherpesviruses: lessons from the mouse.
TL;DR: MHV68 represents a unique model to define the effects of chronic viral infection on the antiviral immune response and available data support a model in which gammaherpesvirus infection drives B cell proliferation and differentiation.
Journal ArticleDOI
Utilization of sialic acid as a coreceptor enhances reovirus attachment by multistep adhesion strengthening.
TL;DR: Results indicate that reovirus binding to sialic acid enhances virus infection through adhesion of virus to the cell surface where access to a proteinaceous receptor is thermodynamically favored.
Journal ArticleDOI
Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier
Fuan Wang,Yiyue Ma,John W. Barrett,Xiujuan Gao,Joy Loh,Erik S. Barton,Herbert W. Virgin,Grant McFadden +7 more
TL;DR: The Erk–interferon–STAT1 signaling cascade elicited by myxoma virus in nonpermissive primary mouse embryo fibroblasts mediates an innate cellular barrier to poxvirus infection.