Esmaa Bouhamida

TL;DR: The intersections of Ca2+ and the therapeutic targeting of cancer cells are explored, summarizing the therapeutic opportunities forCa2+ signal modulators to improve the effectiveness of current anticancer therapies.

TL;DR: The most significant findings corroborating a role for MPT in the etiology of a spectrum of human diseases, including diseases characterized by acute or chronic loss of adult cells and those characterized by neoplastic initiation are summarized.

TL;DR: The current knowledge on mitophagy (and autophagy) mechanisms in the context of heart disease with an important focus on atherosclerosis, ischemic heart disease, cardiomyopathies, heart failure, hypertension, arrhythmia, congenital heart disease and peripheral vascular disease is summarized.

TL;DR: In this article, the authors summarize recent advances describing the importance of autophagy and mitophagy in neurodegenerative diseases, with particular attention given to multiple sclerosis, Parkinson's disease, and Alzheimer's disease.

TL;DR: In this paper, the authors provide an overview of both established and potential, based on evidence in other pathologies, crosstalks between miRNAs and Notch in cellular processes underlying atherosclerosis, myocardial ischemia, heart failure, calcification of aortic valve, and arrhythmias.