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Ester Alvino
Researcher at National Research Council
Publications - 29
Citations - 801
Ester Alvino is an academic researcher from National Research Council. The author has contributed to research in topics: Melanoma & Cell culture. The author has an hindex of 16, co-authored 28 publications receiving 721 citations. Previous affiliations of Ester Alvino include Sapienza University of Rome.
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Journal ArticleDOI
Altered expression of selected microRNAs in melanoma: antiproliferative and proapoptotic activity of miRNA-155.
Lauretta Levati,Ester Alvino,Elena Pagani,Diego Arcelli,Patrizia Caporaso,Sergio Bondanza,Gianpiero Di Leva,Manuela Ferracin,Stefano Volinia,Enzo Bonmassar,Carlo M. Croce,Stefania D'Atri +11 more
TL;DR: The data further support the finding of altered miRNA expression in melanoma cells and establish for the first time that miRNA-155 is a negative regulator of melanoma cell proliferation and survival.
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miR-126&126* restored expressions play a tumor suppressor role by directly regulating ADAM9 and MMP7 in melanoma.
Nadia Felli,Federica Felicetti,Anna Maria Lustri,M. Cristina Errico,Lisabianca Bottero,Alessio Cannistraci,Alessandra De Feo,Marina Petrini,Francesca Pedini,Mauro Biffoni,Ester Alvino,Massimo Negrini,Manuela Ferracin,Gianfranco Mattia,Alessandra Carè +14 more
TL;DR: In this article, the authors showed that miR-126 and miR126* play a tumor suppressor role in human melanoma through direct or indirect repression of several key oncogenic molecules.
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MicroRNA‐155 targets the SKI gene in human melanoma cell lines
Lauretta Levati,Elena Pagani,Sveva Romani,Daniele Castiglia,Eugenia Piccinni,Claudia Covaciu,Patrizia Caporaso,Sergio Bondanza,Francesca Romana Antonetti,Enzo Bonmassar,Fabio Martelli,Ester Alvino,Stefania D'Atri +12 more
TL;DR: The data demonstrate for the first time that SKI is a target of miR‐155 in melanoma, and that impairment of SKI expression is not the leading mechanism involved in the growth‐suppressive effect of mi R‐155 found in this malignancy.
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AKT is activated in an ataxia-telangiectasia and Rad3-related-dependent manner in response to temozolomide and confers protection against drug-induced cell growth inhibition.
Simona Caporali,Lauretta Levati,Giuseppe Starace,Gianluca Ragone,Enzo Bonmassar,Ester Alvino,Stefania D'Atri +6 more
TL;DR: The hypothesis that clinical benefit could be obtained by combining TMZ with inhibitors of the AKT pathway is supported, and the first evidence of a novel function of ATR as an upstream activator of AKT in response to DNA damage induced by O6-guanine-methylating agents is provided.
Journal ArticleDOI
Role of PLZF in melanoma progression
Federica Felicetti,Lisabianca Bottero,Nadia Felli,Gianfranco Mattia,Catherine Labbaye,Ester Alvino,Cesare Peschle,Mario P. Colombo,Alessandra Carè +8 more
TL;DR: Results indicate that PLZF and HOXB7 are functionally independent and that their coupled deregulation may account for most of the alterations described in melanomas.