Ethan Kung

TL;DR: The capabilities of numerical simulations incorporating deformable walls to capture both the vessel wall motion and wave propagation by accurately predicting the changes in the flow and pressure waveforms at various locations down the length of the deformable flow phantoms are demonstrated.

TL;DR: The ability of multi-scale modeling to reproduce patient specific flow conditions under differing physiological states is demonstrated, and it is demonstrated that the same operation performed in two different patients can lead to different hemodynamic characteristics, and that modeling can be used to uncover physiologic changes associated with different clinical conditions.

TL;DR: A protocol to simulate Fontan lower-body exercise using a closed-loop lumped-parameter model describing the entire circulation is developed to offer a foundation for future advances in modeling Fontan exercise, highlight the needs in clinical data collection, and provide clinicians with quantitative reference exercise physiologies for Fontan patients.

TL;DR: Methods to perform in vitro phantom experiments with physiological flows and pressures are demonstrated, showing good agreement between numerically simulated and experimentally measured velocity fields and pressure waveforms in a complex patient-specific AAA geometry.

TL;DR: The authors' moving domain simulations highlights hemodynamic changes in relation to cardiac morphogenesis; thereby, providing a 2-D quantitative approach to complement imaging analysis.