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Eunah Chung
Researcher at Cincinnati Children's Hospital Medical Center
Publications - 23
Citations - 1807
Eunah Chung is an academic researcher from Cincinnati Children's Hospital Medical Center. The author has contributed to research in topics: Kidney development & Nephron. The author has an hindex of 16, co-authored 23 publications receiving 1568 citations. Previous affiliations of Eunah Chung include Seoul National University & University of Cincinnati Academic Health Center.
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Journal ArticleDOI
Six2 and Wnt Regulate Self-Renewal and Commitment of Nephron Progenitors through Shared Gene Regulatory Networks
Joo-Seop Park,Joo-Seop Park,Wenxiu Ma,Lori L. O'Brien,Eunah Chung,Jin Jin Guo,Jr Gang Cheng,M. Todd Valerius,M. Todd Valerius,Jill A. McMahon,Wing Hung Wong,Andrew P. McMahon +11 more
TL;DR: Alternative transcriptional responses associated with Six2 and β-catenin cobinding events occur through non-Lef/Tcf DNA binding mechanisms, highlighting the regulatory complexity downstream of Wnt signaling in the developing mammalian kidney.
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Ginsenoside-Rg1, one of the major active molecules from Panax ginseng, is a functional ligand of glucocorticoid receptor
TL;DR: Results demonstrate that G-Rg1 is a functional ligand of GR, and the growth of FT02B cells was suppressed by G- Rg1 as well as by Dex, each of whose effects were abolished by RU486.
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Phosphorylation of Cdc20 is required for its inhibition by the spindle checkpoint
Eunah Chung,Rey-Huei Chen +1 more
TL;DR: It is shown that Xenopus laevis Cdc20 is phosphorylated at Ser 50, Thr 64, Thr 68 and Thr 79 during mitosis and that mitogen-activated protein kinase (MAPK) contributes to the phosphorylation at Thr 64 or Thr 68.
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A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens
Frederic Sigoillot,Susan Lyman,Susan Lyman,Jeremy F. Huckins,Jeremy F. Huckins,Brittany Susan Adamson,Eunah Chung,Brian Quattrochi,Brian Quattrochi,Randall W. King +9 more
TL;DR: GESS analysis revealed a prominent off-targeted transcript in several screens, including MAD2 (MAD2L1) in a screen for genes required for the spindle assembly checkpoint, and can enhance the validation rate in RNAi screens.
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Single cell dissection of early kidney development: multilineage priming.
TL;DR: An atlas of gene expression patterns in the developing kidney provides powerful evidence that initial organogenesis involves a process of multilineage priming and identifies a surprising number of genes with partially degraded noncoding RNA.