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Evgeniya Vaskova
Researcher at Stanford University
Publications - 17
Citations - 332
Evgeniya Vaskova is an academic researcher from Stanford University. The author has contributed to research in topics: Induced pluripotent stem cell & Medicine. The author has an hindex of 7, co-authored 15 publications receiving 193 citations. Previous affiliations of Evgeniya Vaskova include Russian Academy of Sciences.
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“epigenetic memory” phenomenon in induced pluripotent stem cells
TL;DR: The “epigenetic memory” phenomenon is discussed in the context of the reprogramming process, its influence on iPSC properties, and the possibilities of its application in cell technologies.
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Mitochondria-Rich Extracellular Vesicles From Autologous Stem Cell-Derived Cardiomyocytes Restore Energetics of Ischemic Myocardium.
Gentaro Ikeda,Michelle R. Santoso,Yuko Tada,Albert M. Li,Evgeniya Vaskova,Ji Hye Jung,Connor O'Brien,Elizabeth S. Egan,Jiangbin Ye,Phillip C. Yang +9 more
TL;DR: In this paper, extracellular vesicle (EV)-mediated transfer of autologous mitochondria and their related energy source enhance cardiac function through restoration of myocardial bioenergetics.
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Exosomes From Induced Pluripotent Stem Cell-Derived Cardiomyocytes Promote Autophagy for Myocardial Repair.
Michelle R. Santoso,Gentaro Ikeda,Yuko Tada,Ji Hye Jung,Evgeniya Vaskova,Raymond G. Sierra,Cornelius Gati,Andrew B. Goldstone,Daniel von Bornstaedt,Praveen K. Shukla,Joseph C. Wu,Soichi Wakatsuki,Y. Joseph Woo,Phillip C. Yang +13 more
TL;DR: iCM‐Ex improve post–myocardial infarction cardiac function by regulating autophagy in hypoxic cardiomyoytes, enabling a cell‐free, patient‐specific therapy for ischemic cardiopathy.
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Sacubitril/Valsartan Improves Cardiac Function and Decreases Myocardial Fibrosis Via Downregulation of Exosomal miR‐181a in a Rodent Chronic Myocardial Infarction Model
TL;DR: It is demonstrated that an additional mechanism of action of the pleiotropic effects of sacubitril/valsartan may be mediated by the modulation of the miRNA expression level in the exosome payload.
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Mitochondria-Rich Extracellular Vesicles Rescue Patient-Specific Cardiomyocytes From Doxorubicin Injury: Insights Into the SENECA Trial.
Connor O'Brien,Mehmet Ozgun Ozen,Gentaro Ikeda,Evgeniya Vaskova,Ji Hye Jung,Nathan Bayardo,Michelle R. Santoso,Liye Shi,Christine Wahlquist,Zewen Jiang,Yunshin Jung,Yitian Zeng,Elizabeth S. Egan,Robert Sinclair,Adrian P. Gee,Ronald M. Witteles,Mark Mercola,Katrin J. Svensson,Utkan Demirci,Phillip C. Yang +19 more
TL;DR: An in vitro clinical trial evaluating the efficacy and putative mechanisms of SENECA trial–specific MSCs in treating doxorubicin (DOX) injury suggested a mechanism by which MSC's may improve cardiovascular performance in AIC independent of regeneration, which could inform future trial design evaluating the therapeutic potential of M SCs.