Fabrizio Salvi

TL;DR: It becomes imperative to ascertain the safety of prolonged courses of artemisinin for cancer prophylaxis because of pervasive reports of animal brainstem toxicity, and the gradual emergence of similar patient cases.

TL;DR: Independently from other prognostic factors, patients who received riluzole for a longer period of time survived longer, but further population based studies are needed to verify if long-tem use of rilzole prolongs survival.

TL;DR: Three young patients with transient or intermittent focal neurological signs suggesting brain stem involvement are described, in whom high field MRI showed focal areas of hyperintensity in T2 weighted spin echo images, hypointensity in T 2* weighted gradient echoImages, and enhancement in postcontrast T1 weighted images consistent with unruptured capillary telangiectasia of the brain stem.

TL;DR: Sympathetic Skin Responses (SSR) amplitude was low also in relatives carrying transthyretin (TTR) mutations but without clinical or EMG evidence of polyneuropathy, suggesting SSR is useful in assessing autonomic involvement in FAP, even in preclinical stages.

TL;DR: The results suggest that, although the Portuguese Met 30 carriers might have one founder, the mutation probably recurred in populations in Europe in a similar manner to that reported in Japan.