F
Fanny Guzmán
Researcher at Pontifical Catholic University of Valparaíso
Publications - 164
Citations - 2874
Fanny Guzmán is an academic researcher from Pontifical Catholic University of Valparaíso. The author has contributed to research in topics: Peptide & Epitope. The author has an hindex of 28, co-authored 138 publications receiving 2328 citations. Previous affiliations of Fanny Guzmán include Valparaiso University & Sao Paulo State University.
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Journal ArticleDOI
A g-type lysozyme from the scallop Argopecten purpuratus participates in the immune response and in the stability of the hemolymph microbiota.
Roxana González,D Daniel González,Felipe Stambuk,F. Ramírez,Fanny Guzmán,Luis Mercado,Rodrigo Rojas,Carlos Henríquez,Katherina Brokordt,Paulina Schmitt +9 more
TL;DR: In this article , the authors characterized a g-type lysozyme from the scallop Argopecten purpuratus named ApGlys, which has a molecular weight of 20.07 kDa and an isoelectric point (pI) of 6.49.
Journal ArticleDOI
Immune characterization of a Colombian family cluster with SARS-CoV-2 infection
Wbeimar Aguilar-Jimenez,Lizdany Flórez-Álvarez,Daniel S. Rincón,Damariz Marín-Palma,Alexandra Sanchez-Martinez,Jahnnyer Martínez,María Isabel Zapata,John D. Loaiza,Constanza Cárdenas,Fanny Guzmán,Paula A. Velilla,Natalia A. Taborda,Wildeman Zapata,Juan C. Hernandez,Francisco J. Díaz,María Teresa Rugeles +15 more
TL;DR: Although the proinflammatory response is a hallmark of SARS-CoV-2 infection, other phenotypic and functional alterations in NK cells and CD8+ T cells could be associated with the outcome of COVID-19, however, additional studies are required to understand these alterations and to guide future immunotherapy strategies.
Journal ArticleDOI
Enzymatic and chemical synthesis of new anticoagulant peptides.
Anabella Lucía Origone,Anabella Lucía Origone,Grisel Bersi,Grisel Bersi,Andrés Illanes,Héctor Luis Sturniolo,Constanza Silvina Liggieri,Fanny Guzmán,Sonia Barberis,Sonia Barberis +9 more
TL;DR: The results suggest that two new anticoagulant peptides (Z‐YQQ and YQQ) can be useful for safe pharmaceutical applications, Nevertheless, some aspects related to peptide production should be optimized.
Journal ArticleDOI
Rabbit serum against K1 peptide, an immunogenic epitope of the Trypanosoma cruzi KMP-11, decreases parasite invasion to cells
Juan Camilo Diaz-Soto,Paola Lasso,Fanny Guzmán,Manu Forero-Shelton,María del Carmen Thomas,Manuel Carlos López,Felipe Guhl,Adriana Cuéllar,Concepción J. Puerta,John Mario González +9 more
TL;DR: It is shown that K1, a peptide derived from KMP-11, induced polyclonal antibodies capable of decreasing T. cruzi infection in vitro.
Journal ArticleDOI
Peptides Derived From the α-Core and γ-Core Regions of a Putative Silybum marianum Flower Defensin Show Antifungal Activity Against Fusarium graminearum.
Agustina Fernández,María Laura Colombo,Lucrecia M Curto,Gabriela E. Gómez,Gabriela E. Gómez,José M. Delfino,José M. Delfino,Fanny Guzmán,Laura Susana Bakás,Ismael Malbrán,Ismael Malbrán,Sandra Vairo-Cavalli,Sandra Vairo-Cavalli +12 more
TL;DR: In this article, the putative antimicrobial protein DefSm2, expressed in flowers of the wild plant Silybum marianum, was cloned and analyzed using a 3D template-based model that will serve to support the design of novel antifungal peptides.