F
Fanny Guzmán
Researcher at Pontifical Catholic University of Valparaíso
Publications - 164
Citations - 2874
Fanny Guzmán is an academic researcher from Pontifical Catholic University of Valparaíso. The author has contributed to research in topics: Peptide & Epitope. The author has an hindex of 28, co-authored 138 publications receiving 2328 citations. Previous affiliations of Fanny Guzmán include Valparaiso University & Sao Paulo State University.
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Improvement of enzymatic performance of Asclepias curassavica L. proteases by immobilization. Application to the synthesis of an antihypertensive peptide
Anabella Lucía Origone,Anabella Lucía Origone,Anabella Lucía Origone,Sonia Esther Barberis,Sonia Esther Barberis,Andrés Illanes,Fanny Guzmán,Gerardo Enrique Camí,Constanza Silvina Liggieri,Ronny Martinez,Cintia Claudia Bernal +10 more
TL;DR: Immobilized enzyme performance was evaluated under harsh reaction conditions such as the synthesis of the antihypertensive peptide N-α-CBZ-Val-Gly-OH and best results were attributed to the ability of OGS support to guide the enzyme before covalent attachment, increasing its reactivity.
Journal ArticleDOI
New Synthetic Peptides Conjugated to Gold Nanoclusters: Antibiotic Activity Against Escherichia coli O157:H7 and Methicillin-Resistant Staphylococcus aureus (MRSA).
TL;DR: It is evidenced that these antimicrobial peptides conjugated to AuNC serve as promising agents to combat some multi-resistant bacterial strains and that the specific binding of these antimacterial peptides to gold nanoclusters improves the interaction of these nanostructured systems with the biological target.
Journal ArticleDOI
Immune Modulation Ability of Hepcidin from Teleost Fish
Claudio Alvarez,Paula A. Santana,Nicolas Salinas-Parra,Dina Beltrán,Fanny Guzmán,B. Vega,Félix Acosta,Luis Mercado +7 more
TL;DR: The results showed that hepcidin increased the expression of TNF-α, IL-1β, and IL-10 cytokines in leukocyte cells from trout, and the mRNA expressions of the same cytokines were up-regulated in different immune tissue of sea bass, confirming in vitro results.
Journal ArticleDOI
Molecular characterization and cellular localization of a transmembrane C-type lectin receptor in hemocytes from the scallop Argopecten purpuratus
Varinia Morales-Moya,Felipe Stambuk,Rodolfo Farlora,Fanny Guzmán,Luis Mercado,Katherina Brokordt,Paulina Schmitt +6 more
TL;DR: Results obtained in this study reveal the first transmembrane CLR in scallops and show that ApCLR is present at the surface of hemocytes and increase its transcript availability during the immune challenge, suggesting a potential role in the recognition of microorganisms.
IN VITRO EVALUATION OF ANTIMICROBIAL PEPTIDES AGAINST Mycosphaerella fijiensis MORELET AND THEIR INTERACTION WITH SOME CHEMICAL FUNGICIDES
TL;DR: The in vitro activity of different peptides found that they inhibited fungal mycelial growth and ascospore germination of Mycosphaerella fijiensis and seemed compatible with existing chemical fungicides, having no antagonistic or synergistic effect with these agents.