F
Fanny Guzmán
Researcher at Pontifical Catholic University of Valparaíso
Publications - 164
Citations - 2874
Fanny Guzmán is an academic researcher from Pontifical Catholic University of Valparaíso. The author has contributed to research in topics: Peptide & Epitope. The author has an hindex of 28, co-authored 138 publications receiving 2328 citations. Previous affiliations of Fanny Guzmán include Valparaiso University & Sao Paulo State University.
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Journal ArticleDOI
Plasmodium vivax promiscuous T-helper epitopes defined and evaluated as linear peptide chimera immunogens.
Ivette Caro-Aguilar,Alexandra Rodríguez,J. Mauricio Calvo-Calle,Fanny Guzmán,Patricia de la Vega,Manuel E. Patarroyo,Mary R. Galinski,Alberto Moreno +7 more
TL;DR: The identification and functional characterization of six T-cell epitopes that are present in the merozoite surface protein-1 of Plasmodium vivax and bind promiscuously to four different HLA-DRB1∗ alleles are reported and the potential of multimeric, multistage, and multispecies linear-peptide chimeras containing parasite promiscuous T- cell epitopes for malaria vaccine development is highlighted.
Journal ArticleDOI
KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover
Diego Tapia,Diego Tapia,Tomás Jiménez,Tomás Jiménez,Constanza Zamora,Constanza Zamora,Javier Espinoza,Riccardo Rizzo,Alexis González-Cárdenas,Danitza Fuentes,Sergio Hernández,Viviana A Cavieres,Viviana A Cavieres,Andrea Soza,Andrea Soza,Fanny Guzmán,Gloria Arriagada,Maria-Isabel Yuseff,Gonzalo A. Mardones,Gonzalo A. Mardones,Patricia V. Burgos,Patricia V. Burgos,Alberto Luini,Alfonso González,Alfonso González,Jorge Cancino +25 more
TL;DR: KDEL signaling repositions lysosomes in a complex process termed ‘traffic-induced degradation response for secretion’ (TIDeRS) that connects multiple pathways and Golgi secretion.
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Antimicrobial activity of a new synthetic peptide loaded in polylactic acid or poly(lactic-co-glycolic) acid nanoparticles against Pseudomonas aeruginosa, Escherichia coli O157:H7 and methicillin resistant Staphylococcus aureus (MRSA)
J Cruz,J Cruz,J Flórez,J Flórez,Rodrigo Torres,Mauricio Urquiza,Mauricio Urquiza,Jorge A. Gutierrez,Fanny Guzmán,Claudia Ortiz +9 more
TL;DR: These PLA- and PLGA-NPs presented <10% hemolysis indicating that they are hemocompatible and promising for delivery and protection system of GIBIM-P5S9K peptide.
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During active viscerocutaneous leishmaniasis the anti-P2 humoral response is specifically triggered by the parasite P proteins.
Manuel Soto,Jose M. Requena,Luis Quijada,Sergio O. Angel,Luis Gómez,Fanny Guzmán,Manuel E. Patarroyo,C. Alonso +7 more
TL;DR: The anti‐P antibodies elicited during the Leishmania infection do not recognize the conserved C‐terminal domain of the parasite P proteins, in contrast with the findings reported in Chagas’ disease or systemic lupus erythematosus.
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Cyanobacteria and Eukaryotic Microalgae as Emerging Sources of Antibacterial Peptides.
TL;DR: This review presents an overview of antibacterial peptides isolated from cyanobacteria and microalgae, as well as their synergism and mechanisms of action described so far, and underscores the importance of searching for new natural sources of antibiotics.