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Fanny Guzmán

Researcher at Pontifical Catholic University of Valparaíso

Publications -  164
Citations -  2874

Fanny Guzmán is an academic researcher from Pontifical Catholic University of Valparaíso. The author has contributed to research in topics: Peptide & Epitope. The author has an hindex of 28, co-authored 138 publications receiving 2328 citations. Previous affiliations of Fanny Guzmán include Valparaiso University & Sao Paulo State University.

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Plasmodium vivax promiscuous T-helper epitopes defined and evaluated as linear peptide chimera immunogens.

TL;DR: The identification and functional characterization of six T-cell epitopes that are present in the merozoite surface protein-1 of Plasmodium vivax and bind promiscuously to four different HLA-DRB1∗ alleles are reported and the potential of multimeric, multistage, and multispecies linear-peptide chimeras containing parasite promiscuous T- cell epitopes for malaria vaccine development is highlighted.
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During active viscerocutaneous leishmaniasis the anti-P2 humoral response is specifically triggered by the parasite P proteins.

TL;DR: The anti‐P antibodies elicited during the Leishmania infection do not recognize the conserved C‐terminal domain of the parasite P proteins, in contrast with the findings reported in Chagas’ disease or systemic lupus erythematosus.
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Cyanobacteria and Eukaryotic Microalgae as Emerging Sources of Antibacterial Peptides.

TL;DR: This review presents an overview of antibacterial peptides isolated from cyanobacteria and microalgae, as well as their synergism and mechanisms of action described so far, and underscores the importance of searching for new natural sources of antibiotics.