F
Fanny Roussi
Researcher at Centre national de la recherche scientifique
Publications - 16
Citations - 814
Fanny Roussi is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Alkylation & Lactam. The author has an hindex of 8, co-authored 16 publications receiving 732 citations. Previous affiliations of Fanny Roussi include University of Paris & Institut de Chimie des Substances Naturelles.
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Journal ArticleDOI
Structural basis for the regulation of tubulin by vinblastine
Benoît Gigant,Chunguang Wang,Raimond B. G. Ravelli,Fanny Roussi,Michel O. Steinmetz,Patrick A. Curmi,André Sobel,Marcel Knossow +7 more
TL;DR: The X-ray structure of vinblastine bound to tubulin in a complex with the RB3 protein stathmin-like domain (RB3-SLD) explains vin Blastine-induced tubulin self-association into spiral aggregates at the expense of microtubule growth.
Journal ArticleDOI
Diastereoselective Cycloadditions of Chiral Non-racemic Azomethine Imines
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Isolation of Premyrsinane, Myrsinane, and Tigliane Diterpenoids from Euphorbia pithyusa Using a Chikungunya Virus Cell-Based Assay and Analogue Annotation by Molecular Networking
Mélissa Esposito,Mélissa Esposito,Louis-Félix Nothias,Pascal Retailleau,Jean Costa,Fanny Roussi,Johan Neyts,Pieter Leyssen,David Touboul,Marc Litaudon,Julien Paolini +10 more
TL;DR: Results showed that the 4β-dideoxyphorbol ester 10 was the most active compound, with an EC50 value of 4.0 ± 0.3 μM and a selectivity index of 10.6.
Journal ArticleDOI
Asymmetric 1,3-dipolar cycloadditions of a chiral non-racemic azomethine imine
Fanny Roussi,Martine Bonin,Angèle Chiaroni,Laurent Micouin,Claude Riche,Henri-Philippe Husson +5 more
TL;DR: In this article, the facial, endo exo and regio selectivities of 1,3-dipolar cycloadditions of this reactive species with various dipolarophiles have been studied and described.
Journal ArticleDOI
Investigation of Premyrsinane and Myrsinane Esters in Euphorbia cupanii and Euphobia pithyusa with MS2LDA and Combinatorial Molecular Network Annotation Propagation.
Mélissa Nothias-Esposito,Mélissa Nothias-Esposito,Mélissa Nothias-Esposito,Louis-Félix Nothias,Ricardo Silva,Pascal Retailleau,Zheng Zhang,Pieter Leyssen,Fanny Roussi,David Touboul,Julien Paolini,Pieter C. Dorrestein,Marc Litaudon +12 more
TL;DR: A combinatorial database of theoretical structures was created and used for C-NAP that made possible the annotation of 123 premyrs inane or myrsinane esters, from which 74% are not found in any compound database.