Marc Litaudon

TL;DR: In GNPS, crowdsourced curation of freely available community-wide reference MS libraries will underpin improved annotations and data-driven social-networking should facilitate identification of spectra and foster collaborations.

TL;DR: This work proposes an innovative dereplication strategy based on the combination of MN with an extensive in-silico MS/MS fragmentation database of NPs, and demonstrates that this combined approach offers a powerful tool to navigate through the chemistry of complex NPs extracts, dereplicate metabolites, and annotate analogues of database entries.

TL;DR: The concept of bioactive molecular networking to find candidate active molecules directly from fractionated bioactive extracts to find antiviral compounds from a previously investigated extract of Euphorbia dendroides where the bioactive candidate molecules were not discovered following a classical bioassay-guided fractionation procedure.

TL;DR: Variolin B (1), a new type of pyridopyrrolopyrimidine alkaloid with antitumour and antiviral properties, has been isolated from the Antarctic sponge Kirkpatrickia varialosa, and its structure determined by X-ray crystallography.

TL;DR: In this paper, Baicalein, the active constituent derived from Scutellaria baicalensis Georgi, has been shown to significantly restore the effectiveness of β-lactam antibiotics and tetracycline against MRSA.