F
Farzad Pakdel
Researcher at University of Rennes
Publications - 128
Citations - 8108
Farzad Pakdel is an academic researcher from University of Rennes. The author has contributed to research in topics: Estrogen receptor & Estrogen receptor alpha. The author has an hindex of 49, co-authored 114 publications receiving 7608 citations. Previous affiliations of Farzad Pakdel include Centre national de la recherche scientifique & French Institute of Health and Medical Research.
Papers
More filters
Journal ArticleDOI
Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals.
Helle Raun Andersen,Anna-Maria Andersson,Steven F. Arnold,Herman Autrup,Marianne Barfoed,Nicola Beresford,Poul Bjerregaard,Lisette B. Christiansen,Birgitte Gissel,René Hummel,Eva Cecilie Bonefeld Jørgensen,B. Korsgaard,Rémy Le Guével,Henrik Leffers,John A. McLachlan,Anette Møller,Jesper Bo Nielsen,Nicolás Olea,Anita Oles-Karasko,Farzad Pakdel,Knud Ladegaard Pedersen,Pilar Perez,Niels Erik Skakkebœk,Carlos Sonnenschein,Ana M. Soto,John P. Sumpter,Susan M. Thorpe,Philippe Grandjean +27 more
TL;DR: The aim of this study was to compare results obtained by eight different short-term assays of estrogenlike actions of chemicals conducted in 10 different laboratories in five countries.
Journal ArticleDOI
Molecular Characterization of Three Estrogen Receptor Forms in Zebrafish: Binding Characteristics, Transactivation Properties, and Tissue Distributions
Arnaud Menuet,Elisabeth Pellegrini,Isabelle Anglade,Odile Blaise,Vincent Laudet,Olivier Kah,Farzad Pakdel +6 more
TL;DR: The cloning and characterization of three functional ER forms, zfERα, z fERβ1, and zf ERβ2, in the zebrafish provides a new perspective for understanding the mechanisms underlying estradiol actions in a vertebrate species commonly used for developmental studies.
Journal ArticleDOI
Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish.
TL;DR: Diverse EDCs may affect the expression and/or activity of aromatase cyp19 genes through a variety of mechanisms, many of which need further characterization in order to improve the prediction of risks posed by a contaminated environment to teleost fish population.
Journal ArticleDOI
Aromatase in the brain of teleost fish: expression, regulation and putative functions.
Nicolas Diotel,Yann Le Page,Karen Mouriec,Sok-Keng Tong,Elisabeth Pellegrini,Colette Vaillant,Isabelle Anglade,François Brion,Farzad Pakdel,Bon Chu Chung,Olivier Kah +10 more
TL;DR: In situ hybridization, immunohistochemistry and expression of GFP in transgenic tg(cyp19a1b-GFP) fish demonstrate that aromatase B is only expressed in radial glial cells (RGC) of adult fish, suggesting that it could be part of the mechanisms authorizing the maintenance of a high proliferative activity in the brain of fish.
Journal ArticleDOI
Identification of aromatase-positive radial glial cells as progenitor cells in the ventricular layer of the forebrain in zebrafish.
Elisabeth Pellegrini,Karen Mouriec,Isabelle Anglade,Arnaud Menuet,Yann Le Page,Marie-Madeleine Gueguen,Marie-Hélène Marmignon,François Brion,Farzad Pakdel,Olivier Kah +9 more
TL;DR: The expression of aromatase in the neural stem cells of the adult strongly demonstrates that the fish brain is an outstanding model for studying the effects of estrogens on adult neurogenesis and brain repair.