S
Susan M. Thorpe
Researcher at Novo Nordisk
Publications - 47
Citations - 2023
Susan M. Thorpe is an academic researcher from Novo Nordisk. The author has contributed to research in topics: Breast cancer & Estrogen receptor. The author has an hindex of 25, co-authored 47 publications receiving 1995 citations.
Papers
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Journal ArticleDOI
Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals.
Helle Raun Andersen,Anna-Maria Andersson,Steven F. Arnold,Herman Autrup,Marianne Barfoed,Nicola Beresford,Poul Bjerregaard,Lisette B. Christiansen,Birgitte Gissel,René Hummel,Eva Cecilie Bonefeld Jørgensen,B. Korsgaard,Rémy Le Guével,Henrik Leffers,John A. McLachlan,Anette Møller,Jesper Bo Nielsen,Nicolás Olea,Anita Oles-Karasko,Farzad Pakdel,Knud Ladegaard Pedersen,Pilar Perez,Niels Erik Skakkebœk,Carlos Sonnenschein,Ana M. Soto,John P. Sumpter,Susan M. Thorpe,Philippe Grandjean +27 more
TL;DR: The aim of this study was to compare results obtained by eight different short-term assays of estrogenlike actions of chemicals conducted in 10 different laboratories in five countries.
Journal Article
Association between High Concentrations of Mr 52,000 Cathepsin D and Poor Prognosis in Primary Human Breast Cancer
Susan M. Thorpe,Henri Rochefort,Marcel Garcia,Gilles Freiss,Ib Jarle Christensen,Siham Khalaf,Francis Paolucci,Bernard Pau,Birgitte Bruun Rasmussen,Carsten Rose +9 more
TL;DR: It is demonstrated that the level of Mr 52,000 cathepsin D in cytosol of primary breast cancer biopsies is an independent prognostic factor in predicting relapses in both pre/peri- and postmenopausal patients.
Journal Article
Prognostic value of steroid hormone receptors: multivariate analysis of systemically untreated patients with node negative primary breast cancer.
Susan M. Thorpe,Carsten Rose,Birgitte Bruun Rasmussen,Henning T. Mouridsen,Thomas Bayer,Niels Keiding +5 more
TL;DR: Qualitative assessment of receptor status was as valuable as quantitative expression of receptor concentrations in predicting the RFS of the natural course of the disease among node negative premenopausal patients.
Journal Article
Prognostic Usefulness of Estrogen Receptor Immunocytochemical Assays for Human Breast Cancer
Eugene R. DeSombre,Susan M. Thorpe,Carsten Rose,Richard R. Blough,Andersen Kw,Birgitte Bruun Rasmussen,William King +6 more
TL;DR: It was found that a combination of the distribution of ER-ICA stained cells and the overall staining intensity gave a statistically significant correlation with the quantitative estrogen receptor dextran-coated charcoal steroid binding assay value.
Journal ArticleDOI
Increased use of immunohistochemistry for oestrogen receptor measurement in mammary carcinoma: the need for quality assurance
TL;DR: This paper outlines the changes which have occurred over the last 25 years in the methods employed for the measurement of oestrogen receptors to aid the management of women with breast cancer and discusses the advantages and pitfalls of the immunohistochemical assay.