Felix Beyer

TL;DR: Evidence is provided that FTY720P application supports the generation of a repair promoting cellular phenotype and it is suggested that Fingolimod could be used as treatment for peripheral nerve injuries and diseases.

TL;DR: Evidence is provided for the existence of IANs in PSC-neuronal networks based on extracellular multielectrode array and intracellular patch-clamp recordings, and the intrinsic activity and pacemaker properties of the neuronal subpopulation identified herein may be particularly relevant for interventions involving transplantation of neural tissues.

TL;DR: Bioinformatics and meta‐analysis of high‐throughput datasets are employed to reconstruct a regulatory network underpinning OL differentiation and identify families of feedforward loops comprising the transcription factors (TFs) Olig2, Sox10, and Tcf7l2 and their targets.

TL;DR: This review summarizes and discusses studies, taking into account the different niches, the heterogeneity within and between stem cell niches and present current strategies of how to promote stem cell-mediated myelin repair.

TL;DR: It is shown for the first time that dominant pro‐oligodendroglial factors derived from human fetal MSCs can instruct human induced pluripotent stem cell‐derived NSCs to differentiate into O4 positive oligodendrocytes, and Stimulation with human MSC factors was observed to equally promote rat stem cell oligodendedrogenesis, axonal wrapping and tissue integration.