F
Felix Naef
Researcher at École Polytechnique Fédérale de Lausanne
Publications - 139
Citations - 11496
Felix Naef is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Circadian clock & Circadian rhythm. The author has an hindex of 50, co-authored 135 publications receiving 9961 citations. Previous affiliations of Felix Naef include Swiss Institute of Bioinformatics & École Polytechnique.
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Journal ArticleDOI
Circadian gene expression in individual fibroblasts: cell-autonomous and self-sustained oscillators pass time to daughter cells.
TL;DR: It is demonstrated that in vitro cultured fibroblasts harbor self-sustained and cell-autonomous circadian clocks similar to those operative in SCN neurons, and unexpected interactions between the circadian clock and the cell division clock are unveiled.
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Mammalian genes are transcribed with widely different bursting kinetics
David M. Suter,Nacho Molina,David Gatfield,David Gatfield,Kim Schneider,Ueli Schibler,Felix Naef +6 more
TL;DR: This work established various gene trap cell lines and transgenic cell lines expressing a short-lived luciferase protein from an unstable mRNA, and recorded bioluminescence in real time in single cells, demonstrating that bursting kinetics are highly gene-specific.
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Molecular signature of human embryonic stem cells and its comparison with the mouse
TL;DR: A significant number of HESCs-enriched genes, including several signaling components, are found to be intersected with published mouse embryonic stem cell data, indicating that a "core molecular program" is shared between the two pluripotent stem cells.
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Circadian regulation of gene expression systems in the Drosophila head
Adam Claridge-Chang,Herman Wijnen,Felix Naef,Catharine Boothroyd,Nikolaus Rajewsky,Michael W. Young +5 more
TL;DR: The complement of circadian transcripts in adult Drosophila heads was determined and a subset of 158 genes showed particularly robust cycling and many oscillatory phases, associated with genes involved in diverse biological processes, including learning and memory/synapse function.
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Transport and conservation laws
TL;DR: In this article, the effect of conservation laws on the finite-temperature transport properties in one-dimensional integrable quantum many-body systems was studied and the energy current is closely related to the first conservation law in these systems and therefore the thermal transport coefficients are anomalous.