F
Feng Shen
Researcher at Second Military Medical University
Publications - 403
Citations - 12498
Feng Shen is an academic researcher from Second Military Medical University. The author has contributed to research in topics: Hepatocellular carcinoma & Medicine. The author has an hindex of 46, co-authored 313 publications receiving 8315 citations.
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Journal ArticleDOI
Expression level of Bcl-XL critically affects sensitivity of hepatocellular carcinoma cells to LIGHT-enhanced and interferon-gamma-induced apoptosis.
TL;DR: Insight into the signaling pathways involved in apoptosis induced by IFN-gamma/LIGHT in hepatocellular carcinoma (HCC) cell lines may help to select better therapeutic strategies for certain cancers with distinct Bcl-XL expression.
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Role of β-Catenin in regulating the balance between TNF-α- and Fas-induced acute liver injury
Shan-Shan Zou,Wen Yang,He-Xin Yan,Le-Xing Yu,Yu-Qiong Li,Fu-Quan Wu,Liang Tang,Yan Lin,Lin-Na Guo,Hua-Bang Zhou,Dong-Xun Zhou,Feng Shen,Meng-Chao Wu,He-Ping Hu,Hongyang Wang +14 more
TL;DR: β-Catenin plays an important role in regulating the balance between TNF-α and Fas-induced liver injury via its effect on NF-κB, which aggravates oxidative stress but decreases Fas expression under injury conditions.
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Proposed modification of the eighth edition of the AJCC staging system for intrahepatic cholangiocarcinoma.
Xu Feng Zhang,Feng Xue,Jin He,Sorin Alexandrescu,Hugo Marques,Luca Aldrighetti,Shishir K. Maithel,Carlo Pulitano,Todd W. Bauer,Feng Shen,George A. Poultsides,Oliver Soubrane,Guillaume Martel,Bas Groot Koerkamp,Endo Itaru,Yi Lv,Timothy M. Pawlik +16 more
TL;DR: In this article, a modified version of the 8th edition of the American Joint Committee on Cancer (AJCC) staging system for intrahepatic cholangiocarcinoma (ICC) with establishment and validation of a modified TNM (mTNM) was presented.
Journal ArticleDOI
[Detection of human telomerase activity by telomerase TRAP-ELISA assay].
Lixin Wei,Meng-Chao Wu,Zhenlin Yan,Feng Shen,Tianpei Xie,Qi-jun Qian,Zhenfu Cui,Junxia Shi,Yajun Guo +8 more
TL;DR: In this article, a novel Telomerase TRAP-ELISA assay was developed and evaluated for detecting human telomerase activity, which is a system based on the combination of PCR ELISA with TRAP.
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Multicenter analysis of long-term oncologic outcomes of hepatectomy for elderly patients with hepatocellular carcinoma.
Hao Xing,Lei Liang,Hong Wang,Ya-Hao Zhou,You-Liang Pei,Chao Li,Yongyi Zeng,Wei-Min Gu,Ting-Hao Chen,Jie Li,Yao-Ming Zhang,Ming-Da Wang,Wan-Guang Zhang,Timothy M. Pawlik,Wan Yee Lau,Feng Shen,Meng-Chao Wu,Tian Yang +17 more
TL;DR: Age by itself is not a contraindication to surgery, and selected elderly patients with HCC can benefit from hepatectomy, Compared with younger patients, elderly patients have noninferior oncologic outcomes following hepateCTomy for HCC.