F
Fengfei Ding
Researcher at Huazhong University of Science and Technology
Publications - 27
Citations - 1809
Fengfei Ding is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 7, co-authored 8 publications receiving 1059 citations. Previous affiliations of Fengfei Ding include University of Rochester Medical Center & Oregon Health & Science University.
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Journal ArticleDOI
Impairment of paravascular clearance pathways in the aging brain
Benjamin T. Kress,Jeffrey J. Iliff,Jeffrey J. Iliff,Maosheng Xia,Maosheng Xia,Minghuan Wang,Helen S. Wei,Douglas M. Zeppenfeld,Lulu Xie,Hongyi Kang,Qiwu Xu,Jason Liew,Benjamin A. Plog,Fengfei Ding,Fengfei Ding,Rashid Deane +15 more
TL;DR: Evaluating the efficiency of CSF–ISF exchange and interstitial solute clearance is impaired in the aging brain found that bulk flow drainage via the glymphatic system is driven by cerebrovascular pulsation, and is dependent on astroglial water channels that line paravascular CSF pathways.
Journal ArticleDOI
Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease.
Weiguo Peng,Thiyagarajan M. Achariyar,Baoman Li,Yonghong Liao,Humberto Mestre,Emi Hitomi,Sean Regan,Tristan Kasper,Sisi Peng,Fengfei Ding,Helene Benveniste,Rashid Deane +11 more
TL;DR: It is shown that CSF-derived Aβ40 co-localizes with existing endogenous vascular and parenchymal amyloid-β plaques, and thus, may contribute to the progression of both cerebral amyloids angiopathy andparenchylal Aβ accumulation.
Journal ArticleDOI
Trends in smoking prevalence and implication for chronic diseases in China: serial national cross-sectional surveys from 2003 to 2013.
Minghuan Wang,Xiang Luo,Shabei Xu,Wenhua Liu,Fengfei Ding,Xiaoxiang Zhang,Liang Wang,Jian Liu,Jianping Hu,Wei Wang +9 more
TL;DR: While a consistently high proportion of Chinese men smoked, the standardised smoking prevalence in women younger than 40 years increased from 1·0% in 2003 to 1·6% in 2013, and the association between smoking and chronic diseases by using multiple logistic regression was identified.
Journal ArticleDOI
Focal solute trapping and global glymphatic pathway impairment in a murine model of multiple microinfarcts
Minghuan Wang,Minghuan Wang,Fengfei Ding,Fengfei Ding,Sai Yue Deng,Xuequn Guo,Wei Wang,Jeffrey J. Iliff,Jeffrey J. Iliff +8 more
TL;DR: The findings indicate that glymphatic function is focally disrupted around microinfarcts and that the aging brain is more vulnerable to this disruption than the young brain, and microlesions may trap proteins and other interstitial solutes within the brain parenchyma, increasing the risk of amyloid plaque formation.
Journal ArticleDOI
Clinical Features of Severe Wasp Sting Patients with Dominantly Toxic Reaction: Analysis of 1091 Cases
Cuihong Xie,Shabei Xu,Fengfei Ding,Minjie Xie,Jiagao Lv,Jihua Yao,Dengji Pan,Qian Sun,Chenchen Liu,Tie Chen,Shusheng Li,Weixu Wang +11 more
TL;DR: In China, most patients with multiple wasp stings presented with toxic reactions and multiple organ dysfunction caused by the venom rather than an anaphylactic reaction, and AKI is the prominent clinical manifestation of wasp Stings with toxic reaction.