F
Fenglei He
Researcher at Tulane University
Publications - 30
Citations - 1428
Fenglei He is an academic researcher from Tulane University. The author has contributed to research in topics: Neural crest & Wnt signaling pathway. The author has an hindex of 17, co-authored 27 publications receiving 1247 citations. Previous affiliations of Fenglei He include Ohio State University & Icahn School of Medicine at Mount Sinai.
Papers
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Journal ArticleDOI
Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development.
Fenglei He,Wei Xiong,Wei Xiong,Xueyan Yu,Ramón A. Espinoza-Lewis,Ramón A. Espinoza-Lewis,Chao Liu,Chao Liu,Shuping Gu,Michiru Nishita,Kentaro Suzuki,Gen Yamada,Yasuhiro Minami,Yiping Chen,Yiping Chen +14 more
TL;DR: This work shows that Wnt5a and its receptor Ror2 are expressed in a graded manner along the AP axis of the palate, and reveals distinct regulatory roles for Wnt 5a in gene expression and cell proliferation and an essential role in the regulation of directional cell migration within the developing palate.
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Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5
Ramón A. Espinoza-Lewis,Ling Yu,Fenglei He,Hongbing Liu,Ruhang Tang,Jiangli Shi,Xiaoxiao Sun,James F. Martin,Da-Zhi Wang,Jing Yang,YiPing Chen +10 more
TL;DR: It is demonstrated that Shox2 plays an essential role in the SAN and pacemaker development by controlling a genetic cascade through the repression of Nkx2-5 in the developing heart, leading to a reduced cardiac field and aberrant heart formation.
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Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis
Bing Hu,Karine Lefort,Wenying Qiu,Bach Cuc Nguyen,Renuga Devi Rajaram,Einar Castillo,Fenglei He,YiPing Chen,Peter Angel,Cathrin Brisken,G. Paolo Dotto,G. Paolo Dotto +11 more
TL;DR: It is reported that maintenance of the hair follicle keratinocyte cell fate is defective in mice with mesenchymal deletion of the CSL/RBP-Jkappa gene, the effector of "canonical" Notch signaling.
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Modulation of BMP signaling by Noggin is required for the maintenance of palatal epithelial integrity during palatogenesis.
Fenglei He,Wei Xiong,Ying Wang,Maiko Matsui,Xueyan Yu,Yang Chai,John Klingensmith,YiPing Chen +7 more
TL;DR: It is concluded that Noggin mediated modulation of BMP signaling is essential for palatal epithelium integrity and for normal palate development.
Journal ArticleDOI
Wnt5a regulates growth, patterning, and odontoblast differentiation of developing mouse tooth
Minkui Lin,Lu Li,Chao Liu,Hongbing Liu,Fenglei He,Fuhua Yan,Yanding Zhang,YiPing Chen,YiPing Chen +8 more
TL;DR: It is suggested that Wnt5a regulates growth, patterning, and odontoblast differentiation during odontogenesis, at least partially by modulating Wnt/β‐catenin canonical signaling.