F
Fiona S. L. Brinkman
Researcher at Simon Fraser University
Publications - 150
Citations - 26548
Fiona S. L. Brinkman is an academic researcher from Simon Fraser University. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 64, co-authored 140 publications receiving 22219 citations. Previous affiliations of Fiona S. L. Brinkman include Dalhousie University & University of British Columbia.
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Journal ArticleDOI
Disruption of the Gut Microbiota With Antibiotics Exacerbates Acute Vascular Rejection.
Kevin Rey,Sukhbir Manku,Winnie Enns,Thea Van Rossum,Kevin Bushell,Ryan D. Morin,Fiona S. L. Brinkman,Jonathan C. Choy +7 more
TL;DR: Disruption of the gut microbiota early in life results in exacerbation of immune responses that cause acute vascular rejection, and is related to increased infiltration of allograft arteries by neutrophils.
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Baseline Practices for the Application of Genomic Data Supporting Regulatory Food Safety.
Dominic Lambert,Arthur W. Pightling,Emma Griffiths,Gary Van Domselaar,Peter Evans,Sharon Berthelet,Duncan Craig,P. Scott Chandry,Robert Stones,Fiona S. L. Brinkman,Alexandre Angers-Loustau,Joachim Kreysa,Weida Tong,Burton W. Blais +13 more
TL;DR: General principles to guide the use of NGS data in support of microbiological food safety are outlined, to promote the reliability, consistency, and transparency of processes used in the derivation of genomic information.
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Molecular analyses of disease pathogenesis: application of bovine microarrays.
Heather L. Wilson,Palok Aich,Fiona M. Roche,Shakiba Jalal,P. D. Hodgson,Fiona S. L. Brinkman,Andy Potter,Lorne A. Babiuk,Philip J. Griebel +8 more
TL;DR: Microarray analyses of both host and pathogen responses hold substantial promise for the generation of databases that can be used in the future to address a wide variety of questions and a critical component limiting these comparative analyses will be the quality of the databases and the complete functional annotation of the bovine genome.
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MicrobeDB: a locally maintainable database of microbial genomic sequences
Morgan G. I. Langille,Matthew R. Laird,William W. L. Hsiao,Terry A. Chiu,Jonathan A. Eisen,Fiona S. L. Brinkman +5 more
TL;DR: MicrobeDB provides a foundation for analysis of microbial genomes by the automation of downloading published, completed bacterial and archaeal genomes from key sources, parsing annotations of all genomes into a local database, and allowing interaction with the database through an easy to use programming interface.
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Opinion: Conservation and stewardship of the human microbiome
Kieran C. O’Doherty,Josh D. Neufeld,Fiona S. L. Brinkman,Humphrey Gardner,David S. Guttman,Robert G. Beiko +5 more
TL;DR: It is argued that there is benefit to regarding the global human microbiome as a collective good (i.e., a Microbial Commons) and the situation where each individual benefits from overexploitation of a public resource.