F
Florent Barthas
Researcher at Centre national de la recherche scientifique
Publications - 8
Citations - 642
Florent Barthas is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Neuropathic pain & Allodynia. The author has an hindex of 7, co-authored 7 publications receiving 481 citations. Previous affiliations of Florent Barthas include University of Strasbourg.
Papers
More filters
Journal ArticleDOI
The Anterior Cingulate Cortex Is a Critical Hub for Pain-Induced Depression
Florent Barthas,Jim Sellmeijer,Jim Sellmeijer,Sylvain Hugel,Elisabeth Waltisperger,Michel Barrot,Ipek Yalcin +6 more
TL;DR: The results show that, at cortical level, the sensory component of chronic pain remains functionally segregated from its affective and anxiodepressive components, and constitutes an important target for divulging the underlying mechanism.
Journal ArticleDOI
Emotional consequences of neuropathic pain: insight from preclinical studies.
TL;DR: This review reports the preclinical evidences from anatomical, neuroimaging, behavioral, pharmacological and biochemical studies that address the anxiodepressive consequences of neuropathic pain and presents an overview of rodent models of these consequences.
Journal ArticleDOI
Hyperactivity of Anterior Cingulate Cortex Areas 24a/24b Drives Chronic Pain-Induced Anxiodepressive-like Consequences.
Jim Sellmeijer,Jim Sellmeijer,Jim Sellmeijer,Victor Mathis,Sylvain Hugel,Xu-Hui Li,Qian Song,Qi-Yu Chen,Florent Barthas,Pierre-Eric Lutz,Meltem Karatas,Andreas Lüthi,Pierre Veinante,Ad Aertsen,Michel Barrot,Min Zhuo,Min Zhuo,Ipek Yalcin +17 more
TL;DR: It is shown that the mechanical hypersensitivity, ongoing pain, anxiodepressive consequences, and their recoveries do not necessarily exhibit temporal synchrony during chronic pain processing, and that the hyperactivity of the anterior cingulate cortex is essential for driving the emotional impact of neuropathic pain.
Journal ArticleDOI
The sciatic nerve cuffing model of neuropathic pain in mice.
Ipek Yalcin,Salim Megat,Florent Barthas,Elisabeth Waltisperger,Mélanie Kremer,Eric Salvat,Michel Barrot +6 more
TL;DR: The detailed surgery procedure for the "cuff model" of neuropathic pain in mice is described, a cuff of PE-20 polyethylene tubing of standardized length is unilaterally implanted around the main branch of the sciatic nerve and induces a long-lasting mechanical allodynia.
Journal ArticleDOI
Cingulate Overexpression of Mitogen-Activated Protein Kinase Phosphatase-1 as a Key Factor for Depression
Florent Barthas,Muris Humo,Ralf Gilsbach,Elisabeth Waltisperger,Meltem Karatas,Samuel Leman,Lutz Hein,Catherine Belzung,Anne-Laurence Boutillier,Michel Barrot,Ipek Yalcin +10 more
TL;DR: Gene expression changes in the anterior cingulate cortex highlighted the overexpression of a regulator of the mitogen-activated protein kinase pathway, MKP-1, suggesting an important role of this phosphatase in depression.