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Catherine Belzung

Researcher at François Rabelais University

Publications -  224
Citations -  22604

Catherine Belzung is an academic researcher from François Rabelais University. The author has contributed to research in topics: Hippocampal formation & Anxiogenic. The author has an hindex of 65, co-authored 213 publications receiving 20246 citations. Previous affiliations of Catherine Belzung include French Institute of Health and Medical Research & University of Strasbourg.

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Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants

TL;DR: It is shown that disrupting antidepressant-induced neurogenesis blocks behavioral responses to antidepressants, suggesting that the behavioral effects of chronic antidepressants may be mediated by the stimulation of neuroGenesis in the hippocampus.
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The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review

TL;DR: Compounds that have a different spectrum of therapeutic efficacy in anxiety disorders such as panic attacks, generalized anxiety disorder or obsessive-compulsive disorder were poorly effective as anxiolytics in the open field test, suggesting that this paradigm may not model features of anxiety disorders.
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Measuring normal and pathological anxiety-like behaviour in mice: a review.

TL;DR: When assessing the behaviour of mice, it is necessary to increase the range of behavioural paradigms used, including animal models of "state" and "trait" anxiety.
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Decreased GABA A -receptor clustering results in enhanced anxiety and a bias for threat cues

TL;DR: The γ2+/– mice represent a model of anxiety characterized by harm avoidance behavior and an explicit memory bias for threat cues, resulting in heightened sensitivity to negative associations.
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Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal.

TL;DR: It is suggested that hippocampal neurogenesis might be used by the monoaminergic ADs to counteract the effects of stress, whereas similar effects could be achieved by directly targeting the HPA axis and related neuropeptides.