F
Francesca Ricci
Researcher at University of Brescia
Publications - 78
Citations - 2734
Francesca Ricci is an academic researcher from University of Brescia. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 28, co-authored 64 publications receiving 2438 citations. Previous affiliations of Francesca Ricci include University of Bologna & Humanitas University.
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Journal ArticleDOI
CTLA‐4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction
Elisabetta Contardi,Giulio Lelio Palmisano,Pier Luigi Tazzari,Alberto M. Martelli,Federica Fala,Marina Fabbi,Tomohiro Kato,Enrico Lucarelli,Davide Maria Donati,Letizia Polito,Andrea Bolognesi,Francesca Ricci,Sandra Salvi,Vittoria Gargaglione,Stefano Mantero,Marco Alberghini,Giovanni Battista Ferrara,Maria Pia Pistillo +17 more
TL;DR: The novel finding that CTLA‐4 molecule is expressed and functional on human tumor cells opens up the possibility of antitumor therapeutic intervention based on targeting this molecule.
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Activity of the Novel Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 against T-Cell Acute Lymphoblastic Leukemia
Francesca Chiarini,Cecilia Grimaldi,Francesca Ricci,Pier Luigi Tazzari,Camilla Evangelisti,Andrea Ognibene,Michela Battistelli,Elisabetta Falcieri,Fraia Melchionda,Andrea Pession,Pasqualepaolo Pagliaro,James A. McCubrey,Alberto M. Martelli +12 more
TL;DR: Results indicate that longitudinal inhibition at two nodes of the PI3K/Akt/mTOR network with NVP-BEZ235, either alone or in combination with chemotherapeutic drugs, may be an efficient treatment of those T-ALLs that have aberrant upregulation of this signaling pathway for their proliferation and survival.
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Alemtuzumab As Consolidation After a Response to Fludarabine Is Effective in Purging Residual Disease in Patients With Chronic Lymphocytic Leukemia
Marco Montillo,Alessandra Tedeschi,Sara Miqueleiz,Silvio Veronese,Roberto Cairoli,Liliana Intropido,Francesca Ricci,Anna Colosimo,Barbara Scarpati,Michela Montagna,Michele Nichelatti,Mario Regazzi,Enrica Morra +12 more
TL;DR: Subcutaneously administered alemtuzumab was effective, safe, and well tolerated as consolidation therapy in patients with CLL who responded to fludarabine induction therapy.
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Dual inhibition of class IA phosphatidylinositol 3-kinase and mammalian target of rapamycin as a new therapeutic option for T-cell acute lymphoblastic leukemia.
Francesca Chiarini,Federica Fala,Pier Luigi Tazzari,Francesca Ricci,Annalisa Astolfi,Andrea Pession,Pasqualepaolo Pagliaro,James A. McCubrey,Alberto M. Martelli +8 more
TL;DR: Analysis of the therapeutic potential of the dual PI3K/mTOR inhibitor PI-103 indicates that multitargeted therapy towardPI3K and mTOR alone or with existing drugs may serve as an efficient treatment toward T-ALL cells, which require up-regulation of PI3k/Akt/m TOR signaling for their survival and growth.
Journal ArticleDOI
Thoracic aortas from multiorgan donors are suitable for obtaining resident angiogenic mesenchymal stromal cells.
Gianandrea Pasquinelli,Pier Luigi Tazzari,C. Vaselli,Laura Foroni,Marina Buzzi,Gianluca Storci,Francesco Alviano,Francesca Ricci,Massimiliano Bonafè,Catia Orrico,Gian Paolo Bagnara,Andrea Stella,Roberto Conte +12 more
TL;DR: It is demonstrated that thoracic aortas from multiorgan donors yield mesenchymal stromal cells with the ability to differentiate in vitro into endothelial cells, thus providing new options for restoring vascularization at ischemic sites.