G
Giovanni Battista Ferrara
Researcher at University of Genoa
Publications - 63
Citations - 3816
Giovanni Battista Ferrara is an academic researcher from University of Genoa. The author has contributed to research in topics: Human leukocyte antigen & Antigen. The author has an hindex of 26, co-authored 63 publications receiving 3459 citations. Previous affiliations of Giovanni Battista Ferrara include Mario Negri Institute for Pharmacological Research & National Cancer Research Institute.
Papers
More filters
Journal ArticleDOI
Tryptophan-derived Catabolites Are Responsible for Inhibition of T and Natural Killer Cell Proliferation Induced by Indoleamine 2,3-Dioxygenase
Guido Frumento,Rita Rotondo,Michela Tonetti,Gianluca Damonte,Umberto Benatti,Giovanni Battista Ferrara,Giovanni Battista Ferrara +6 more
TL;DR: It is suggested that IDO exerts its effect on cell proliferation by starting the cascade of biochemical reactions that produce the three catabolites and by enhancing their inhibitory potential by depriving the extracellular microenvironment of tryptophan.
Journal ArticleDOI
CTLA‐4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction
Elisabetta Contardi,Giulio Lelio Palmisano,Pier Luigi Tazzari,Alberto M. Martelli,Federica Fala,Marina Fabbi,Tomohiro Kato,Enrico Lucarelli,Davide Maria Donati,Letizia Polito,Andrea Bolognesi,Francesca Ricci,Sandra Salvi,Vittoria Gargaglione,Stefano Mantero,Marco Alberghini,Giovanni Battista Ferrara,Maria Pia Pistillo +17 more
TL;DR: The novel finding that CTLA‐4 molecule is expressed and functional on human tumor cells opens up the possibility of antitumor therapeutic intervention based on targeting this molecule.
Journal ArticleDOI
Stromal damage as consequence of high-dose chemo/radiotherapy in bone marrow transplant recipients.
Maria Galotto,G. Berisso,Laura Delfino,Marina Podestà,Laura Ottaggio,Sandro Dallorso,Carlo Dufour,Giovanni Battista Ferrara,Angelo Abbondandolo,Giorgio Dini,Andrea Bacigalupo,Ranieri Cancedda,Rodolfo Quarto +12 more
TL;DR: It is demonstrated that the marrow stromal microenvironment is seriously and irreversibly damaged after BMT, and donor cells do not contribute to reconstitute the marrow microenvironment, whose residual CFU-fs remain of host origin.
Journal ArticleDOI
A combination of a particular HLA-DPβ allele and an HLA-DQ heterodimer confers susceptibility to coeliac disease
Teodorica L. Bugawan,Giovanna Angelini,James W. Larrick,Salvatore Auricchio,Giovanni Battista Ferrara,Henry A. Erlich +5 more
TL;DR: A new DNA-based method of HLA-DP typing is used to analyse the distribution of DPβ alleles in a group of coeliac disease patients and healthy controls and suggests that the polymorphic residues at position 69 and at 56 and 57 may be critical in conferring susceptibility.
Journal ArticleDOI
Evidence that celiac disease is primarily associated with a DC locus allelic specificity
Roberto Tosi,Daniela Vismara,Nobuyuki Tanigaki,Giovanni Battista Ferrara,Filippo Cicimarra,Wilma Buffolano,Daniela Follo,Salvatore Auricchio +7 more
TL;DR: Celiac disease is primarily associated with the DC determinant and the previously described associations with DR3, DR7, B8, B13, and A1 can be explained by decreasing degrees of linkage disequilibrium with DC3.