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Jochen Seufert

Researcher at University of Freiburg

Publications -  186
Citations -  9074

Jochen Seufert is an academic researcher from University of Freiburg. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 33, co-authored 162 publications receiving 6867 citations. Previous affiliations of Jochen Seufert include University Medical Center Freiburg.

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Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.

TL;DR: In patients with type 2 diabetes who were at high cardiovascular risk, the rate of cardiovascular death, nonfatal myocardial infarction, orNonfatal stroke was significantly lower among patients receiving semaglutide than among those receiving placebo, an outcome that confirmed the noninferiority of semag lutide.
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Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial

Adrian F. Hernandez, +798 more
- 27 Oct 2018 - 
TL;DR: In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events, and evidence-based glucagon-like peptide 1 receptor agonists should be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events.
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Physiology and role of irisin in glucose homeostasis

TL;DR: This Review presents the current knowledge on the physiology of irisin and its role in glucose homeostasis, and describes the mechanisms involved in the synthesis, secretion, circulation and regulation of irisin, and the controversies regarding the measurement.
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Effects of high glucose on mesenchymal stem cell proliferation and differentiation.

TL;DR: HG (25mM) enhanced h MSC-TERT proliferation in long-term studies in contrast to hMSC where proliferation was unchanged, and thioredoxin-interacting protein, which is involved in apoptosis regulation, was stimulated by glucose in hMSc-TERt, however, apoptosis was not influenced by HG in both cell types.
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Sequential Intensification of Metformin Treatment in Type 2 Diabetes With Liraglutide Followed by Randomized Addition of Basal Insulin Prompted by A1C Targets

TL;DR: In this article, the authors evaluated the addition of liraglutide to metformin in type 2 diabetes followed by intensification with basal insulin (detemir) if glycated hemoglobin (A1C) ≥ 7%.