F
Franck Letourneur
Researcher at Paris Descartes University
Publications - 21
Citations - 972
Franck Letourneur is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 15, co-authored 21 publications receiving 861 citations. Previous affiliations of Franck Letourneur include French Institute of Health and Medical Research.
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Journal ArticleDOI
On the diversity of malaria parasites in African apes and the origin of Plasmodium falciparum from Bonobos.
Sabrina Krief,Ananias A. Escalante,M. Andreína Pacheco,Lawrence Mugisha,Claudine André,Michel Halbwax,Anne Fischer,Jean Michel Krief,John M. Kasenene,Mike Crandfield,Omar E. Cornejo,Jean Marc Chavatte,Clara Lin,Franck Letourneur,Anne Charlotte Grüner,Anne Charlotte Grüner,Thomas F. McCutchan,Laurent Rénia,Laurent Rénia,Georges Snounou +19 more
TL;DR: Phylogenetic analyses based on this diverse set of Plasmodium parasites in African Apes shed new light on the evolutionary history of P. falciparum, and indicated that chimpanzees and bonobos maintain malaria parasites, to which humans are susceptible, a factor of some relevance to the renewed efforts to eradicate malaria.
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A genome-wide approach reveals novel imprinted genes expressed in the human placenta
Sandrine Barbaux,Géraldine Gascoin-Lachambre,Christophe Buffat,Paul Monnier,Françoise Mondon,Marie-Béatrice Tonanny,Amélie Pinard,Jana Auer,Bettina Bessières,Anne Barlier,Sébastien Jacques,Umberto Simeoni,Luisa Dandolo,Franck Letourneur,Hélène Jammes,Daniel Vaiman +15 more
TL;DR: The number of known imprinted genes in humans is increased by about 10% using a high-throughput strategy by diverting the classical use of genotyping microarrays to compare the genotypes of mRNA/cDNA vs. genomic DNA to identify new genes presenting monoallelic expression, starting from human placental material.
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In Vitro Fertilization and Embryo Culture Strongly Impact the Placental Transcriptome in the Mouse Model
Patricia Fauque,Françoise Mondon,Françoise Mondon,Franck Letourneur,Marie-Anne Ripoche,Marie-Anne Ripoche,Laurent Journot,Sandrine Barbaux,Sandrine Barbaux,Luisa Dandolo,Luisa Dandolo,Catherine Patrat,Jean-Philippe Wolf,Pierre Jouannet,Hélène Jammes,Hélène Jammes,Hélène Jammes,Daniel Vaiman,Daniel Vaiman +18 more
TL;DR: For the first time, in vitro fertilization associated with embryo culture strongly modify the placental expression profile, long after embryo manipulations, meaning that the stress of artificial environment is memorized after implantation.
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Epicutaneous immunotherapy (EPIT) blocks the allergic esophago-gastro-enteropathy induced by sustained oral exposure to peanuts in sensitized mice.
Lucie Mondoulet,Vincent Dioszeghy,Thibaut Larcher,Mélanie Ligouis,Véronique Dhelft,Emilie Puteaux,Yan Cherel,Franck Letourneur,Christophe Dupont,Pierre-Henri Benhamou +9 more
TL;DR: Gastro-intestinal lesions induced by sustained oral exposure to peanuts in sensitized mice are efficaciously treated by allergen specific EPIT.
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Intact skin and not stripped skin is crucial for the safety and efficacy of peanut epicutaneous immunotherapy (EPIT) in mice
Lucie Mondoulet,Vincent Dioszeghy,Emilie Puteaux,Mélanie Ligouis,Véronique Dhelft,Franck Letourneur,Christophe Dupont,Pierre-Henri Benhamou +7 more
TL;DR: Epicutaneous allergen-specific immunotherapy needs the integrity of superficial layers of the stratum corneum to warranty safety of treatment and to induce a tolerogenic profile of the immune response.