In Vitro Fertilization and Embryo Culture Strongly Impact the Placental Transcriptome in the Mouse Model
Patricia Fauque,Françoise Mondon,Françoise Mondon,Franck Letourneur,Marie-Anne Ripoche,Marie-Anne Ripoche,Laurent Journot,Sandrine Barbaux,Sandrine Barbaux,Luisa Dandolo,Luisa Dandolo,Catherine Patrat,Jean-Philippe Wolf,Pierre Jouannet,Hélène Jammes,Hélène Jammes,Hélène Jammes,Daniel Vaiman,Daniel Vaiman +18 more
Reads0
Chats0
TLDR
For the first time, in vitro fertilization associated with embryo culture strongly modify the placental expression profile, long after embryo manipulations, meaning that the stress of artificial environment is memorized after implantation.Abstract:
Background
Assisted Reproductive Technologies (ART) are increasingly used in humans; however, their impact is now questioned. At blastocyst stage, the trophectoderm is directly in contact with an artificial medium environment, which can impact placental development. This study was designed to carry out an in-depth analysis of the placental transcriptome after ART in mice.read more
Citations
More filters
Journal Article
Assisted reproductive technology.
TL;DR: Assisted reproductive technology (ART) is the technology used to achieve pregnancy in procedures such as fertility medication, artificial insemination, in vitro fertilization and surrogacy.
Journal ArticleDOI
Epigenetics and the placenta
TL;DR: Epigenetic regulation of the placenta evolves during preimplantation development and further gestation and appears to be involved in the pathogenesis of pre-eclampsia and GTD.
Journal ArticleDOI
Expert consensus document: Clinical and molecular diagnosis, screening and management of Beckwith-Wiedemann syndrome: an international consensus statement.
Frédéric Brioude,Jennifer M. Kalish,Alessandro Mussa,Alison Foster,Alison Foster,Jet Bliek,Giovanni Battista Ferrero,Susanne E Boonen,Trevor Cole,Robert Baker,Monica Bertoletti,Guido Cocchi,Carole Coze,Maurizio De Pellegrin,Khalid Hussain,Abdulla Ibrahim,Mark D. Kilby,Mark D. Kilby,Małgorzata Krajewska-Walasek,Christian P. Kratz,Edmund J. Ladusans,Pablo Lapunzina,Yves Le Bouc,Saskia M. Maas,Fiona Macdonald,Katrin Õunap,Licia Peruzzi,Sylvie Rossignol,Silvia Russo,Caroleen Shipster,Agata Skórka,Katrina Tatton-Brown,Jair Tenorio,Chiara Tortora,Karen Grønskov,Irène Netchine,Raoul C.M. Hennekam,Dirk Prawitt,Zeynep Tümer,Thomas Eggermann,Deborah J G Mackay,Andrea Riccio,Eamonn R. Maher +42 more
TL;DR: An international consensus group agreed upon 72 recommendations for the clinical and molecular diagnosis and management of Beckwith–Wiedemann syndrome, including comprehensive protocols for the molecular investigation, care and treatment of patients from the prenatal period to adulthood.
Journal ArticleDOI
Infertility and reproductive disorders: impact of hormonal and inflammatory mechanisms on pregnancy outcome
Silvia Vannuccini,Vicki L. Clifton,Ian S. Fraser,Hugh S. Taylor,Hilary O. D. Critchley,Linda C. Giudice,Felice Petraglia +6 more
TL;DR: There is a real need for development of evidence-based recommendations about clinical management and specific obstetric care pathways for the introduction of prompt preventative care measures.
Journal ArticleDOI
Further evidence that culture media affect perinatal outcome: findings after transfer of fresh and cryopreserved embryos
Ewka C.M. Nelissen,Aafke P.A. van Montfoort,Edith Coonen,Josien G. Derhaag,Joep P.M. Geraedts,Luc J.M. Smits,Jolande A. Land,Johannes L.H. Evers,John C.M. Dumoulin +8 more
TL;DR: The hypothesis that in vitro culture of embryos during the first few days of preimplantation development affects perinatal outcome of IVF singletons and twins is supported and might be an important factor explaining the poorer perinnatal outcome after assisted reproduction technology (ART).
References
More filters
Journal ArticleDOI
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources.
TL;DR: By following this protocol, investigators are able to gain an in-depth understanding of the biological themes in lists of genes that are enriched in genome-scale studies.
Journal ArticleDOI
A review: James H. Meisel, The Fall of the Republic: Military Revolt in France Edward R. Tannenbaum, The Action Française: Diehard Reactionaries in Twentieth-Century France
Journal ArticleDOI
DAVID: Database for Annotation, Visualization, and Integrated Discovery
Glynn Dennis,Brad T. Sherman,Douglas A. Hosack,Jun Jun Yang,Wei Gao,H. Clifford Lane,Richard A. Lempicki +6 more
TL;DR: DAMID is a web-accessible program that integrates functional genomic annotations with intuitive graphical summaries that assists in the interpretation of genome-scale datasets by facilitating the transition from data collection to biological meaning.
Journal ArticleDOI
Summaries of Affymetrix GeneChip probe level data
Rafael A. Irizarry,Benjamin M. Bolstad,Francois Collin,Leslie Cope,Bridget G. Hobbs,Terence P. Speed,Terence P. Speed +6 more
TL;DR: It is found that the performance of the current version of the default expression measure provided by Affymetrix Microarray Suite can be significantly improved by the use of probe level summaries derived from empirically motivated statistical models.
Journal ArticleDOI
The KEGG databases at GenomeNet
TL;DR: The Kyoto Encyclopedia of Genes and Genomes (KEGG) is the primary database resource of the Japanese GenomeNet service for understanding higher order functional meanings and utilities of the cell or the organism from its genome information.