F
Franck Polleux
Researcher at Columbia University
Publications - 114
Citations - 11287
Franck Polleux is an academic researcher from Columbia University. The author has contributed to research in topics: Axon & Biological neural network. The author has an hindex of 49, co-authored 102 publications receiving 9644 citations. Previous affiliations of Franck Polleux include Columbia University Medical Center & French Institute of Health and Medical Research.
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Journal ArticleDOI
AMP-activated protein kinase mediates mitochondrial fission in response to energy stress
Erin Quan Toyama,Sébastien Herzig,Julien Courchet,Tommy L. Lewis,Oliver C. Losón,Kristina Hellberg,Nathan P. Young,Hsiuchen Chen,Franck Polleux,David C. Chan,Reuben J. Shaw +10 more
TL;DR: The energy-sensing adenosine monophosphate (AMP)–activated protein kinase (AMPK) is genetically required for cells to undergo rapid mitochondrial fragmentation after treatment with ETC inhibitors and direct pharmacological activation of AMPK was sufficient to rapidly promote mitochondrial fragmentation even in the absence of mitochondrial stress.
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Semaphorin 3A is a chemoattractant for cortical apical dendrites
TL;DR: In this paper, it was shown that the growth of apical dendrites towards the pial surface is regulated by a diffusible chemoattractant present at high levels near the marginal zone.
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Establishment of axon-dendrite polarity in developing neurons
Anthony P. Barnes,Franck Polleux +1 more
TL;DR: The recent data supporting an integrative model whereby extracellular cues orchestrate the intracellular signaling underlying the initial break of neuronal symmetry leading to axon-dendrite polarization are synthesized.
Journal ArticleDOI
LKB1 and SAD Kinases Define a Pathway Required for the Polarization of Cortical Neurons
Anthony P. Barnes,Brendan N. Lilley,Y. Albert Pan,Lisa J. Plummer,Ashton W. Powell,Alexander N. Raines,Joshua R. Sanes,Franck Polleux +7 more
TL;DR: Evidence is provided in vivo and in vitro for a multikinase pathway that links extracellular signals to the intracellular machinery required for axon specification during neuronal polarization in the mammalian cerebral cortex.
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Control of cortical interneuron migration by neurotrophins and PI3-kinase signaling.
TL;DR: It is found that MGE-derived cells migrate through the entire extent of the cortex and into the CA fields of the hippocampus, but avoid the dentate gyrus, suggesting that TrkB signaling, via PI3-kinase activation, plays an important role in controlling interneuron migration in the developing cerebral cortex.