François Blanquart

TL;DR: Practical recommendations are provided regarding the definition of local adaptation, the analysis of transplant experiments and the optimisation of the experimental design ofLocal adaptation studies to provide a unified approach for measuring local adaptation and understanding the adaptive divergence of populations in a wide range of biological systems.

TL;DR: Heterogeneity in duration of carriage is a partial explanation for the coexistence of sensitive and resistant strains and that factors determining bacterialduration of carriage will also affect the prevalence of resistance.

TL;DR: In this article, the authors developed mathematical models and used them to generate analytical predictions for the level of local adaptation as a function of selection, migration and genetic drift, and they extended this analysis to cases where the trait under selection is continuous using classical quantitative genetics theory.

TL;DR: This work uses evolve‐and‐resequence experiments with bacteria and yeast to dissect the drivers of parallel evolution at the gene level and presents a modeling approach to estimate the contributions of mutational and selective heterogeneity across a genome to parallel evolution.

TL;DR: The emergence of SARS-CoV-2 variant 20I/501Y.V1 (VOC-202012/1) is concerning given its increased transmissibility as discussed by the authors.