F
Frank E. Speizer
Researcher at Brigham and Women's Hospital
Publications - 641
Citations - 140522
Frank E. Speizer is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Relative risk & Risk factor. The author has an hindex of 193, co-authored 636 publications receiving 135891 citations. Previous affiliations of Frank E. Speizer include Medical Research Council & Beth Israel Deaconess Medical Center.
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Journal ArticleDOI
Body Weight, Weight Change, and Risk for Hypertension in Women
Zhiping Huang,Walter C. Willett,JoAnn E. Manson,Bernard Rosner,Meir J. Stampfer,Frank E. Speizer,Graham A. Colditz +6 more
TL;DR: This study prospectively investigated body mass index at 18 years of age and at midlife, as well as long-term and medium-term weight changes, in relation to subsequent risk for hypertension in a large cohort of U.S. female nurses without diagnosed hypertension.
Journal ArticleDOI
Effects of inhalable particles on respiratory health of children.
Douglas W. Dockery,Frank E. Speizer,Daniel O. Stram,James H. Ware,John D. Spengler,Benjamin G. Ferris +5 more
TL;DR: Examination of data from a second cross-sectional assessment of the association of air pollution with chronic respiratory health of children participating in the Six Cities Study of Air Pollution and Health suggests that children with hyperreactive airways may be particularly susceptible to other respiratory symptoms when exposed to these pollutants.
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A prospective study of maturity-onset diabetes mellitus and risk of coronary heart disease and stroke in women.
JoAnn E. Manson,Graham A. Colditz,Meir J. Stampfer,Walter C. Willett,Andrzej S. Krolewski,Bernard Rosner,Ronald A. Arky,Frank E. Speizer,Charles H. Hennekens +8 more
TL;DR: It is shown that maturity-onset clinical diabetes is a strong determinant of coronary heart disease, ischemic stroke, and cardiovascular mortality among middle-aged women and the adverse effect of diabetes is amplified in the presence of other cardiovascular risk factors.
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Plasma sex steroid hormone levels and risk of breast cancer in postmenopausal women.
Susan E. Hankinson,Walter C. Willett,JoAnn E. Manson,Graham A. Colditz,David J. Hunter,Donna Spiegelman,Robert L. Barbieri,Frank E. Speizer +7 more
TL;DR: The data, in conjunction with past epidemiologic and animal studies, provide strong evidence for a causal relationship between postmenopausal estrogen levels and the risk of breast cancer.
Journal ArticleDOI
Dietary Fiber and the Risk of Colorectal Cancer and Adenoma in Women
Charles S. Fuchs,Edward Giovannucci,Graham A. Colditz,David J. Hunter,Meir J. Stampfer,Bernard Rosner,Frank E. Speizer,Walter C. Willett +7 more
TL;DR: The data do not support the existence of an important protective effect of dietary fiber against colorectal cancer or adenoma against women with no history of cancer, inflammatory bowel disease, or familial polyposis.