F
Frank E. Speizer
Researcher at Brigham and Women's Hospital
Publications - 641
Citations - 140522
Frank E. Speizer is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Relative risk & Risk factor. The author has an hindex of 193, co-authored 636 publications receiving 135891 citations. Previous affiliations of Frank E. Speizer include Medical Research Council & Beth Israel Deaconess Medical Center.
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Journal ArticleDOI
Circulating concentrations of insulin-like growth factor I and risk of breast cancer
Susan E. Hankinson,Walter C. Willett,Walter C. Willett,Graham A. Colditz,Graham A. Colditz,David J. Hunter,David J. Hunter,Dominique S. Michaud,Dominique S. Michaud,Bonnie Deroo,Bernard Rosner,Frank E. Speizer,Michael Pollak +12 more
TL;DR: A positive relation between circulating IGF-I concentration and risk of breast cancer was found among premenopausal but not postmenopausal women, and may be useful in the identification of women at high risk of Breast cancer and in the development of risk reduction strategies.
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The use of estrogens and progestins and the risk of breast cancer in postmenopausal women.
Graham A. Colditz,Susan E. Hankinson,David J. Hunter,Walter C. Willett,JoAnn E. Manson,Meir J. Stampfer,Charles H. Hennekens,Bernard Rosner,Frank E. Speizer +8 more
TL;DR: In this paper, the effect of adding progestins to estrogen therapy on the risk of breast cancer in postmenopausal women is investigated. But, the effect on the number of newly diagnosed invasive breast cancer cases was not quantified.
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The Effect of Fruit and Vegetable Intake on Risk for Coronary Heart Disease
KKaumudi J Joshipura,Frank B. Hu,JoAnn E. Manson,Meir J. Stampfer,Eric B. Rimm,Frank E. Speizer,Graham A. Colditz,Alberto Ascherio,Bernard Rosner,Donna Spiegelman,Walter C. Willett +10 more
TL;DR: A 1-serving/d increase in fruit or vegetable intake was associated with a 6% lower risk for ischemic stroke, after controlling for standard cardiovascular risk factors, and analyses limited to confirmed cases yielded results very similar to those obtained when all cases were included.
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A prospective study of obesity and risk of coronary heart disease in women.
JoAnn E. Manson,Graham A. Colditz,Meir J. Stampfer,Walter C. Willett,Bernard Rosner,Richard R. Monson,Frank E. Speizer,Charles H. Hennekens +7 more
TL;DR: Even mild-to-moderate overweight increased the risk of coronary disease in middle-aged women, and the importance of obesity as a determinant of coronary heart disease in women is emphasized.
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Reduction in fine particulate air pollution and mortality : Extended Follow-up of the Harvard Six Cities Study
TL;DR: Total, cardiovascular, and lung cancer mortality were each positively associated with ambient PM2.5 concentrations.