F
Friedrich Lottspeich
Researcher at Max Planck Society
Publications - 449
Citations - 31053
Friedrich Lottspeich is an academic researcher from Max Planck Society. The author has contributed to research in topics: Peptide sequence & Amino acid. The author has an hindex of 94, co-authored 449 publications receiving 30250 citations. Previous affiliations of Friedrich Lottspeich include Technische Universität Darmstadt & University of Marburg.
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Journal ArticleDOI
Molecular cloning and expression of brain-derived neurotrophic factor.
Joachim Leibrock,Friedrich Lottspeich,Hohn Andreas,Magdalena Hofer,Bastian Hengerer,Piotr Masiakowski,Hans Thoenen,Yves-Alain Barde +7 more
TL;DR: The full primary structure of brain-derived neurotrophic factor is reported and it is established that these two neurotrophic factors are related both functionally and structurally.
Journal ArticleDOI
Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1
TL;DR: It is shown that Esp1 causes the dissociation of Scc1 from chromosomes by stimulating its cleavage by proteolysis, and a mutant SCC1 is described that is resistant to Esp1-dependent cleavage and which blocks both sister-chromatid separation and the dissociations from chromosomes.
PatentDOI
Ciliary neurotrophic factor
Piotr Masiakowski,Vivien Wong,Nikos Panayotatos,Hans Thoenen,Stockli-Rippstein Kurt A,Michael Sendtner,Yoshihiro Arakawa,Patrick Carroll,Rudolf Götz,Georg W. Kreutzberg,Dan Lindholm,Friedrich Lottspeich,Nancy Y. Ip,Mark E. Furth +13 more
TL;DR: In this article, the authors proposed a method for cloning and expression of ciliary neurotrophic factor (CNTF) and provided a means for producing human CNTF utilizing human CCL-encoding nucleic acid sequences.
Journal ArticleDOI
A novel strategy for quantitative proteomics using isotope‐coded protein labels
TL;DR: A novel method, termed isotope‐coded protein label (ICPL), which is capable of high‐throughput quantitative proteome profiling on a global scale, and based on stable isotope tagging at the frequent free amino groups of isolated intact proteins, applicable to any protein sample.
Journal ArticleDOI
Neurotrophin-6 is a new member of the nerve growth factor family.
Rudolf Götz,Reinhard W. Köster,Christoph Winkler,F. Raulf,Friedrich Lottspeich,Manfred Schartl,Hans Thoenen +6 more
TL;DR: The cloning of neurotrophin-6 (NT-6), a new mem-ber of this family from the teleost fish Xiphophorus is reported, which has a spectrum of actions similar to NGF on chick sympathetic and sensory neurons, albeit with a lower potency.