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Friedrich Lottspeich

Researcher at Max Planck Society

Publications -  449
Citations -  31053

Friedrich Lottspeich is an academic researcher from Max Planck Society. The author has contributed to research in topics: Peptide sequence & Amino acid. The author has an hindex of 94, co-authored 449 publications receiving 30250 citations. Previous affiliations of Friedrich Lottspeich include Technische Universität Darmstadt & University of Marburg.

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Journal ArticleDOI

Molecular cloning and expression of brain-derived neurotrophic factor.

TL;DR: The full primary structure of brain-derived neurotrophic factor is reported and it is established that these two neurotrophic factors are related both functionally and structurally.
Journal ArticleDOI

Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1

TL;DR: It is shown that Esp1 causes the dissociation of Scc1 from chromosomes by stimulating its cleavage by proteolysis, and a mutant SCC1 is described that is resistant to Esp1-dependent cleavage and which blocks both sister-chromatid separation and the dissociations from chromosomes.
PatentDOI

Ciliary neurotrophic factor

TL;DR: In this article, the authors proposed a method for cloning and expression of ciliary neurotrophic factor (CNTF) and provided a means for producing human CNTF utilizing human CCL-encoding nucleic acid sequences.
Journal ArticleDOI

A novel strategy for quantitative proteomics using isotope‐coded protein labels

TL;DR: A novel method, termed isotope‐coded protein label (ICPL), which is capable of high‐throughput quantitative proteome profiling on a global scale, and based on stable isotope tagging at the frequent free amino groups of isolated intact proteins, applicable to any protein sample.
Journal ArticleDOI

Neurotrophin-6 is a new member of the nerve growth factor family.

TL;DR: The cloning of neurotrophin-6 (NT-6), a new mem-ber of this family from the teleost fish Xiphophorus is reported, which has a spectrum of actions similar to NGF on chick sympathetic and sensory neurons, albeit with a lower potency.