F
Fu-Ping Zhang
Researcher at University of Helsinki
Publications - 30
Citations - 3291
Fu-Ping Zhang is an academic researcher from University of Helsinki. The author has contributed to research in topics: luteinizing hormone/choriogonadotropin receptor & Gonadotropin. The author has an hindex of 22, co-authored 27 publications receiving 3060 citations. Previous affiliations of Fu-Ping Zhang include University of Turku.
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Journal ArticleDOI
Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice.
TL;DR: The LuRKO mouse is a close phenocopy of recently characterized human patients with inactivating LHR mutations, although the lack of pseudohermaphroditism in LuR KO males suggests that the intrauterine sex differentiation in this species is not dependent on LH action.
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Novel Expression and Functional Role of Ghrelin in Rat Testis
Manuel Tena-Sempere,M.L. Barreiro,LC Gonzalez,F Gaytan,Fu-Ping Zhang,Jorge E. Caminos,Leonor Pinilla,Felipe F. Casanueva,Carlos Dieguez,Enrique Aguilar +9 more
TL;DR: The present results underscore an unexpected role of ghrelin as signal with ability to potentially modulate not only growth and body weight homeostasis but also reproductive function, a phenomenon also demonstrated recently for the adipocyte-derived hormone, leptin.
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Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures
Sofia Movérare-Skrtic,Petra Henning,Xianwen Liu,Kenichi Nagano,Hiroaki Saito,Anna E Börjesson,Klara Sjögren,Sara H Windahl,Helen H. Farman,Bert Kindlund,Cecilia Engdahl,Antti Koskela,Fu-Ping Zhang,Emma Eriksson,Farasat Zaman,Ann Hammarstedt,Hanna Isaksson,Marta Bally,Ali Kassem,Catharina Lindholm,Olof Sandberg,Per Aspenberg,Lars Sävendahl,Jian Q. Feng,Jan Tuckermann,Juha Tuukkanen,Matti Poutanen,Roland Baron,Ulf H. Lerner,Francesca Gori,Claes Ohlsson +30 more
TL;DR: It is demonstrated here that Wnt16-deficient mice develop spontaneous fractures as a result of low cortical thickness and high cortical porosity, which opens new avenues for the specific prevention or treatment of nonvertebral fractures, a substantial unmet medical need.
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Androgen receptor and androgen-dependent gene expression in lung.
TL;DR: It is shown that Ar is mainly expressed in type II pneumocytes and the bronchial epithelium of murine lung and that androgen treatment increases AR protein levels in lung cells and suggests that AR plays a role in lung cancer biology.
Journal ArticleDOI
Sumo-1 Function Is Dispensable in Normal Mouse Development
Fu-Ping Zhang,Laura Mikkonen,Jorma Toppari,Jorma J. Palvimo,Irma Thesleff,Olli A. Jänne,Olli A. Jänne +6 more
TL;DR: The results support the notion that most, if not all, Sumo-1 functions are compensated for in vivo by SUMO-2 andSumo-3, and that the development and function of testis are normal in the absence of SumO-1.