F
Fujiang Guo
Researcher at Shanghai University
Publications - 57
Citations - 685
Fujiang Guo is an academic researcher from Shanghai University. The author has contributed to research in topics: Agonist & Medicine. The author has an hindex of 12, co-authored 48 publications receiving 477 citations.
Papers
More filters
Journal ArticleDOI
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-γ and PPAR-α agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice.
Li Feng,Huan Luo,Zhijian Xu,Zhuo Yang,Guoxin Du,Yu Zhang,Lijing Yu,Kaifeng Hu,Weiliang Zhu,Qingchun Tong,Kaixian Chen,Kaixian Chen,Fujiang Guo,Cheng Huang,Yiming Li +14 more
TL;DR: This is the first report of a synergistic glucose- and lipid-lowering effect of BVC and synthetic agonists induced by unique binding with PPAR-γ or -α, which may improve the efficacy and decrease the toxicity of marketed drugs for use as adjunctive therapy to treat the metabolic syndrome.
Journal ArticleDOI
Iridoid glycosides isolated from Scrophularia dentata Royle ex Benth. and their anti-inflammatory activity
Liuqiang Zhang,Tiantian Zhu,Fei Qian,Jin-Wen Xu,Gaawe Dorje,Zhili Zhao,Fujiang Guo,Yiming Li +7 more
TL;DR: Bioassay showed that compounds 7 and 11 had significant inhibitory effect against NF-κB activation with IC50 value of 43.7 μM and 1.02 μM respectively.
Journal ArticleDOI
Advances in studying of the pharmacological activities and structure-activity relationships of natural C-glycosylflavonoids
Peng Zeng,Yong Zhang,Chen Pan,Qi Jia,Fujiang Guo,Yiming Li,Weiliang Zhu,Kaixian Chen,Kaixian Chen +8 more
TL;DR: A review of the biological effects of various C -glycosylflavonoids and their structure-activity relationships can be found in this article, where the authors focus on the biological properties of C-GloSs.
Journal ArticleDOI
Prenylflavone derivatives from Broussonetia papyrifera, inhibit the growth of breast cancer cells in vitro and in vivo
TL;DR: Two new prenylflavones from B. Papyrifera exhibit potent anti-tumor activity and compounds 2 and 5 strongly down-regulated expression concentrations of estrogen receptor-α and were able to inhibit tumor growth in a xenograft model of the human breast cancer line BCAP-37 in vivo.
Journal ArticleDOI
Characterization of total phenolic constituents from the stems of Spatholobus suberectus using LC-DAD-MS(n) and their inhibitory effect on human neutrophil elastase activity.
TL;DR: This is the first report on occurrence of most B-type procyanidins in this herb and the total phenolics extract was assayed for inhibitory activity on human neutrophil elastase and its IC50 was found to be 1.33 μg/mL.