G
Gabriel N. Hortobagyi
Researcher at University of Texas MD Anderson Cancer Center
Publications - 1415
Citations - 115570
Gabriel N. Hortobagyi is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 166, co-authored 1374 publications receiving 104845 citations. Previous affiliations of Gabriel N. Hortobagyi include University of Texas System & University of Texas Medical Branch.
Papers
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Journal ArticleDOI
Ki-67 immunostaining in node-negative stage I/II breast carcinoma. Significant correlation with prognosis
Aysegul A. Sahin,Jae Y. Ro,Adel K. El-Naggar,Nelson G. Ordóñez,Alberto G. Ayala,Jungsil Ro,Gabriel N. Hortobagyi,Mark Blick,Herbert A. Fritsche,Terry L. Smith +9 more
TL;DR: The results suggest that Ki‐67 immunostaining correlates well with nuclear grade and clinical outcome in node‐negative breast carcinoma, and both 5‐year disease‐free and overall survivals were strongly associated with percentage of cells stained with Ki‐ 67 antibody.
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Chemotherapy of metastatic breast cancer: What to expect in 2001 and beyond
Francisco J. Esteva,Vicente Valero,Lajos Pusztai,Laura Boehnke-Michaud,Aman U. Buzdar,Gabriel N. Hortobagyi +5 more
TL;DR: Novel cytotoxic therapy strategies include the development of anthracycline, taxane, and oral fluoropyrimidine analogues; antifolates; topoisomerase I inhibitors, and multidrug resistance inhibitors; a better understanding of the biology of breast cancer is providing novel treatment approaches.
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Molecular predictors of response to trastuzumab and lapatinib in breast cancer
TL;DR: It will be important to characterize mechanisms of resistance in metastatic tumors to determine which novel targeted therapy will be most appropriate for individual patients.
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Imaging Bone Metastases in Breast Cancer: Techniques and Recommendations for Diagnosis
Colleen M. Costelloe,Eric M. Rohren,John E. Madewell,Tsuyoshi Hamaoka,Richard L. Theriault,Tse Kuan Yu,Valerae O. Lewis,Jingfei Ma,R. Jason Stafford,Ana M. Tari,Gabriel N. Hortobagyi,Naoto T. Ueno +11 more
TL;DR: Recent innovations in bone imaging are discussed and algorithms are presented, based on the strengths and weaknesses of each technique, to facilitate the most successful and cost-effective choice of imaging studies for the detection of osseous metastases.
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Relationship between obesity and pathologic response to neoadjuvant chemotherapy among women with operable breast cancer
Jennifer K. Litton,Ana M. Gonzalez-Angulo,Carla L. Warneke,Aman U. Buzdar,Shu Wan Kau,Melissa L. Bondy,Somdat Mahabir,Gabriel N. Hortobagyi,Abenaa M. Brewster +8 more
TL;DR: Higher BMI was associated with worse pCR to neoadjuvant chemotherapy in women with operable breast cancer and its association with worse overall survival suggests that greater attention should be focused on this risk factor to optimize the care of breast cancer patients.