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Ralph Burkhardt

Researcher at University Hospital Regensburg

Publications -  141
Citations -  3901

Ralph Burkhardt is an academic researcher from University Hospital Regensburg. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 25, co-authored 116 publications receiving 2479 citations. Previous affiliations of Ralph Burkhardt include Leipzig University & University of Regensburg.

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The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany

TL;DR: The objective is to investigate prevalences, early onset markers, genetic predispositions, and the role of lifestyle factors of major civilization diseases, with primary focus on metabolic and vascular diseases, heart function, cognitive impairment, brain function, depression, sleep disorders and vigilance dysregulation, retinal and optic nerve degeneration, and allergies.

A catalog of genetic loci associated with kidney function from analyses of a million individuals

Matthias Wuttke, +327 more
TL;DR: Trans-ancestry meta-analysis of estimated glomerular filtration rate (eGFR) from 1,046,070 individuals identifies 264 associated loci, providing a resource of molecular targets for translational research of chronic kidney disease.
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Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

Adrienne Tin, +251 more
- 01 Oct 2019 - 
TL;DR: A trans-ancestry genome-wide association study of serum urate levels identifies 183 loci that improve the prediction of gout in an independent cohort of 334,880 individuals, and implicates the kidney and liver as key target organs and prioritize potential causal genes.
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Myocardial Infarction-Associated Circular RNA Predicting Left Ventricular Dysfunction.

TL;DR: Identification of patients at risk of developing left ventricular remodeling and dysfunction after acute myocardial infarction would represent a major step forward toward personalized medicine.
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Genetic architecture of subcortical brain structures in 38,851 individuals

Claudia L. Satizabal, +375 more
- 21 Oct 2019 - 
TL;DR: This paper identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus, globus pallidus, putamen and thalamus using genome-wide association analyses in almost 40,000 individuals from CHARGE, ENIGMA and UK Biobank.