G
Gaëlle Bruneteau
Researcher at University of Paris
Publications - 61
Citations - 2458
Gaëlle Bruneteau is an academic researcher from University of Paris. The author has contributed to research in topics: Amyotrophic lateral sclerosis & SMA*. The author has an hindex of 25, co-authored 55 publications receiving 2030 citations. Previous affiliations of Gaëlle Bruneteau include Paris Descartes University & French Institute of Health and Medical Research.
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Journal ArticleDOI
SOD1, ANG, VAPB, TARDBP, and FUS mutations in familial amyotrophic lateral sclerosis: genotype–phenotype correlations
Stéphanie Millecamps,François Salachas,Cécile Cazeneuve,Paul H. Gordon,Bernard Bricka,Agnès Camuzat,Lena Guillot-Noel,Odile Russaouen,Gaëlle Bruneteau,Pierre-François Pradat,Nadine Le Forestier,Nadia Vandenberghe,Véronique Danel-Brunaud,Nathalie Guy,Christel Thauvin-Robinet,Lucette Lacomblez,Philippe Couratier,Didier Hannequin,Danielle Seilhean,Isabelle Le Ber,Philippe Corcia,William Camu,Alexis Brice,Guy A. Rouleau,Eric LeGuern,Vincent Meininger +25 more
TL;DR: Clinical comparison of SOD1, TARDBP, FUS and other familial ALS patients (with no mutation in the screened genes) revealed differences in site of onset, age of onset (younger with FUS mutations), and in lifespan (shorter for FUS carriers).
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Phenotype difference between ALS patients with expanded repeats in C9ORF72 and patients with mutations in other ALS-related genes
Stéphanie Millecamps,Séverine Boillée,Isabelle Le Ber,Danielle Seilhean,Elisa Teyssou,Marine Giraudeau,Carine Moigneu,Nadia Vandenberghe,Véronique Danel-Brunaud,Philippe Corcia,Pierre-François Pradat,Nadine Le Forestier,Lucette Lacomblez,Gaëlle Bruneteau,William Camu,Alexis Brice,Cécile Cazeneuve,Eric LeGuern,Vincent Meininger,François Salachas +19 more
TL;DR: The results confirm the major role of expanded repeats in C9ORF72 as causative for ALS and provide evidence for specific phenotypic aspects compared to patients with other ALS-related genes.
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Causes of death in a post‐mortem series of ALS patients
Philippe Corcia,Pierre-François Pradat,François Salachas,Gaëlle Bruneteau,Nadine Le Forestier,Danielle Seilhean,Jean-Jacques Hauw,Vincent Meininger +7 more
TL;DR: A retrospective pathological study on 100 ALS patients referred for a deterioration of their clinical condition and who died in the ALS clinic of Salpétrière found that broncho‐pneumonia and pneumonia were the main causes of death, and heart failure was two times more frequent in bulbar than in spinal ALS.
Journal ArticleDOI
Impaired glucose tolerance in patients with amyotrophic lateral sclerosis.
Pierre-François Pradat,Gaëlle Bruneteau,Paul H. Gordon,Luc Dupuis,Dominique Bonnefont-Rousselot,Dominique Simon,François Salachas,Philippe Corcia,Vincent Frochot,Jean-Marc Lacorte,Claude Jardel,Christiane Coussieu,Nadine Le Forestier,Lucette Lacomblez,Jean-Philippe Loeffler,Vincent Meininger +15 more
TL;DR: Patients with ALS show abnormal glucose tolerance that could be associated with increased FFA levels, a key determinant of insulin resistance, and the origin of glucose homeostasis abnormalities in ALS may be multifactorial and deserves further investigation.
Journal ArticleDOI
Progression in ALS is not linear but is curvilinear
Paul H. Gordon,Bin Cheng,François Salachas,Pierre-François Pradat,Gaëlle Bruneteau,Philippe Corcia,Lucette Lacomblez,Vincent Meininger +7 more
TL;DR: The aim of the study is to determine the shape of the progression curve in ALS, assess the impact of clinical variables on the rate of progression, and evaluate the association between functional decline and survival.