Gaelle Chapuis

TL;DR: In this article, the authors designed a task for head-fixed mice that combines established assays of perceptual and value-based decision making, and standardized training protocol and experimental hardware, software, and procedures.

TL;DR: In this article, a task for head-fixed mice that assays perceptual and value-based decision making was adopted, and the training protocol and experimental hardware, software, and procedures were standardized.

TL;DR: It is shown that a standardized task to probe decision-making in mice produces reproducible results across multiple laboratories, and this work establishes a standard for reproducible rodent behavior and indicates a path towards achieving reproducibility in neuroscience through collaborative open-science approaches.

TL;DR: It is found that neuronal yield, firing rates, spike amplitudes, and task-modulated neuronal activity were reproducible across laboratories, and across-lab standardization of electrophysiological procedures can lead to reproducible results across labs.

TL;DR: A novel, modular architecture is reported that allows users to contribute, access, and analyze data across this collaboration of ten experimental labs spanning 7 geographically distributed sites to measure neural activity across the brains of mice making perceptual decisions.