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Nicholas A. Steinmetz
Researcher at University of Washington
Publications - 85
Citations - 8449
Nicholas A. Steinmetz is an academic researcher from University of Washington. The author has contributed to research in topics: Visual cortex & Sensory system. The author has an hindex of 30, co-authored 73 publications receiving 5284 citations. Previous affiliations of Nicholas A. Steinmetz include University of Pennsylvania & University College London.
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Journal ArticleDOI
Fully integrated silicon probes for high-density recording of neural activity
James J. Jun,Nicholas A. Steinmetz,Nicholas A. Steinmetz,Nicholas A. Steinmetz,Joshua H. Siegle,Daniel J. Denman,Marius Bauza,Brian Barbarits,Albert K. Lee,Costas A. Anastassiou,Costas A. Anastassiou,Alexandru Andrei,Cagatay Aydin,Mladen Barbic,Timothy J. Blanche,Vincent Bonin,João Couto,B. Dutta,Sergey L. Gratiy,Diego A. Gutnisky,Michael Häusser,Bill Karsh,Peter Ledochowitsch,Carolina Mora Lopez,Catalin Mitelut,Catalin Mitelut,Silke Musa,Michael S. Okun,Michael S. Okun,Michael S. Okun,Marius Pachitariu,Marius Pachitariu,Jan Putzeys,P. Dylan Rich,Cyrille Rossant,Cyrille Rossant,Wei-Lung Sun,Karel Svoboda,Matteo Carandini,Kenneth D. Harris,Kenneth D. Harris,Christof Koch,John O'Keefe,Timothy D. Harris +43 more
TL;DR: The fully integrated functionality and small size of Neuropixels probes allowed large populations of neurons from several brain structures to be recorded in freely moving animals and opens a path towards recording of brain-wide neural activity during behaviour.
Journal ArticleDOI
Spontaneous behaviors drive multidimensional, brainwide activity.
Carsen Stringer,Marius Pachitariu,Nicholas A. Steinmetz,Charu Bai Reddy,Matteo Carandini,Kenneth D. Harris +5 more
TL;DR: In this article, the authors observed that spontaneous activity reliably encoded a high-dimensional latent state, which was partially related to the mouse's ongoing behavior and was represented not just in visual cortex but also across the forebrain.
Posted ContentDOI
Kilosort: realtime spike-sorting for extracellular electrophysiology with hundreds of channels
TL;DR: Kilosort models the recorded voltage as a sum of template waveforms triggered on the spike times, allowing overlapping spikes to be identified and resolved and is an important step towards fully automated spike sorting of multichannel electrode recordings.
Journal ArticleDOI
Distributed coding of choice, action and engagement across the mouse brain
TL;DR: Recordings from 30,000 neurons in 42 brain regions are used to delineate the spatial distribution of neuronal activity underlying vision, choice, action and behavioural engagement in mice and reveal organizing principles for the distribution of neurons encoding behaviourally relevant variables across the mouse brain.
Journal ArticleDOI
Diverse coupling of neurons to populations in sensory cortex
Michael S. Okun,Michael S. Okun,Michael S. Okun,Nicholas A. Steinmetz,Lee Cossell,Lee Cossell,M. Florencia Iacaruso,M. Florencia Iacaruso,Ho Ko,Ho Ko,Péter Barthó,Tirin Moore,Sonja B. Hofer,Sonja B. Hofer,Thomas D. Mrsic-Flogel,Thomas D. Mrsic-Flogel,Matteo Carandini,Kenneth D. Harris,Kenneth D. Harris,Kenneth D. Harris +19 more
TL;DR: Recordings from the visual cortex of mouse and monkey are used to investigate the relationship between individual neurons and the population, and to establish the underlying circuit mechanisms, showing that neighbouring neurons can differ in their coupling to the overall firing of the population.